Children with congenital hypothyroidism can usually get married when they grow up, but lifelong medication is needed to control the condition. Marriage and childbirth require endocrine assessment and genetic counseling under the guidance of a doctor, with a focus on thyroid function stability, fertility assessment, and genetic risk control.
Patients with congenital hypothyroidism can maintain thyroid hormone levels within the normal range through standardized treatment, and their physical and intellectual development is no different from that of ordinary people. Adult gonadal function is usually not affected, and male sperm quality and female ovulation function are not significantly different from healthy individuals with normal thyroid function. However, it is important to regularly monitor the levels of thyroid stimulating hormone and free thyroid hormone to avoid hormonal fluctuations affecting reproductive system function. Pregnant female patients should have their thyroid function rechecked every 4 weeks and adjust the dosage of levothyroxine sodium tablets in a timely manner to prevent damage to the fetal nervous system development. A very small number of patients with other genetic metabolic diseases or pituitary lesions may experience delayed gonadal development or decreased fertility. This type of situation requires chromosome examination, pituitary MRI, and other methods to determine the cause, and some patients may require assisted reproductive technology intervention. If there is congenital hypothyroidism caused by genetic mutations, it is recommended that spouses undergo thyroid function screening to evaluate the genetic probability of offspring. Patients with severe intellectual disabilities or multiple deformities need to have their marital feasibility evaluated by a specialist doctor. Patients with congenital hypothyroidism should maintain regular medication and regular check ups, and establish a health record to record changes in hormone levels in adulthood. Pay attention to balanced iodine nutrition in daily life but avoid excessive intake. During pregnancy, increase protein and iron intake. It is recommended to complete comprehensive examinations such as thyroid ultrasound and six sex hormone tests before marriage and childbearing of appropriate age. Both spouses should receive genetic counseling, and newborns should undergo heel blood screening within 72 hours after giving birth. Maintaining an optimistic attitude and moderate exercise can help maintain endocrine stability and social activities are not limited by illness.
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