Platelets may fluctuate during menstrual check ups, but the fluctuation amplitude is usually small. The platelet count may slightly decrease due to menstrual bleeding, or briefly increase due to the body's stress response. The impact of menstrual cycle on platelets is mainly related to changes in hormone levels and physiological blood loss caused by endometrial shedding. During menstruation, due to increased secretion of prostaglandins and contraction of endometrial blood vessels, some women may experience increased platelet aggregation, leading to a false increase in platelet count in blood tests. At the same time, menstrual bleeding can stimulate the active hematopoietic function of the bone marrow. Young and healthy women can usually replenish platelets in a short period of time to maintain the values near the lower limit of the normal range. If there is a history of iron deficiency anemia or excessive menstrual flow, platelets may show a transient decrease trend, but the decrease is mostly within 10%. A small number of women with long-term excessive menstrual flow, adenomyosis, and abnormal coagulation function may experience repeated chronic blood loss, which may lead to insufficient iron reserves and subsequently affect platelet production. During physical examinations, this group of people may find that their platelet count remains below normal, accompanied by compensatory changes such as an increase in average platelet volume. In addition, some women may experience mild platelet dysfunction during premenstrual periods due to a sudden drop in estrogen levels, but this condition usually does not significantly affect platelet count test results.

It is recommended to avoid blood routine tests on the 2-3 days with the highest menstrual flow, and to maintain sufficient sleep and a balanced diet before the physical examination. If abnormal platelet values are found, a follow-up examination can be conducted 3-5 days after the end of menstruation. Pay attention to observing the menstrual cycle, changes in menstrual flow, and whether there are symptoms such as gum bleeding and skin bruising in daily life. If necessary, perform related tests such as coagulation function and iron metabolism.


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