Drugs that can lower heart rate but not blood pressure can be chosen from beta 1 receptor blockers, calcium channel blockers, and If channel inhibitors. These drugs selectively act on the heart, reducing heart rate without significantly affecting blood pressure. Beta 1 receptor blockers such as metoprolol, atenolol, and bisoprolol mainly reduce heart rate and cardiac output by inhibiting cardiac beta 1 receptors. Calcium channel blockers such as verapamil and diltiazem block cardiac calcium channels, reducing heart rate and myocardial contractility. If channel inhibitors such as ivabradine lower heart rate by inhibiting sinus node If currents.

β 1 receptor blockers are commonly used heart rate lowering drugs that selectively act on the heart's β 1 receptors without affecting vascular smooth muscle, and therefore do not significantly lower blood pressure. Metoprolol is suitable for patients with hypertension and rapid heart rate, while atenolol is commonly used for angina and arrhythmia, and bisoprolol is used for chronic heart failure and hypertension. These medications should be used under the guidance of a doctor to avoid sudden cessation of medication causing rapid rebound heart rate.

Calcium channel blockers block cardiac calcium channels, reduce heart rate and myocardial contractility, while dilating coronary arteries and improving myocardial blood supply. Verapamil is suitable for paroxysmal supraventricular tachycardia and atrial fibrillation, while diltiazem is used for angina pectoris and hypertension. This type of medication may cause constipation and low blood pressure, and should be closely monitored.
If channel inhibitor ivabradine reduces heart rate by inhibiting sinus node If current, making it suitable for patients with sinus rhythm and high heart rate. This drug does not affect myocardial contractility and blood pressure, and is suitable for patients with heart failure and angina pectoris. Common side effects include visual abnormalities and bradycardia, which require regular follow-up examinations.

Drugs that lower heart rate but not blood pressure should be selected according to the specific situation of the patient. Beta 1 receptor blockers, calcium channel blockers, and If channel inhibitors are commonly used drugs. These drugs lower heart rate through different mechanisms and are suitable for different disease states. During use, it is important to pay attention to the side effects of the medication and regularly check heart rate and blood pressure to ensure treatment effectiveness and safety.
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