The persistent high blood pressure that cannot be lowered may be related to various factors such as genetics, environment, physiological factors, and pathological conditions, and requires comprehensive management through medication, lifestyle adjustments, and medical interventions.

1. Genetic factors play an important role in hypertension, and individuals with a family history of hypertension have a higher risk of developing the disease. For this group of people, it is recommended to regularly monitor blood pressure and consult a doctor to see if medication intervention is needed in advance.
2. environmental factors such as high salt diet, lack of exercise, and long-term stress can also lead to elevated blood pressure. Reduce salt intake and keep the daily salt intake below 5 grams; Increase exercise and engage in 150 minutes of moderate intensity aerobic exercise per week; Relieve stress through meditation, deep breathing, and other methods. 3. Physiological factors such as obesity, aging, and changes in hormone levels can also affect blood pressure. Control weight and maintain a BMI between 18.5-24.9; As one grows older, regular physical examinations should be conducted to monitor changes in blood pressure; Women should pay attention to the rationality of hormone replacement therapy after menopause.
4. Pathological conditions such as kidney disease, endocrine disorders, etc. may cause secondary hypertension. If blood pressure continues to not decrease, it is necessary to investigate related diseases and treat the primary disease.

5. Drug therapy is an important means of controlling hypertension. Common medications include diuretics such as hydrochlorothiazide, calcium channel blockers such as amlodipine, ACE inhibitors such as enalapril, etc. It is necessary to choose appropriate medication under the guidance of a doctor and persist in taking it.
6. Lifestyle adjustments are equally crucial. Eat more foods rich in potassium and magnesium, such as bananas and spinach; Reduce the intake of saturated fat and cholesterol. Quit smoking, limit alcohol consumption, avoid staying up late, and maintain a regular schedule. If blood pressure cannot be controlled through medication and lifestyle adjustments, further medical intervention should be considered. If conducting dynamic blood pressure monitoring, evaluate whether it is necessary to adjust the treatment plan; Or lower blood pressure through interventional treatments such as renal artery ablation.
Long term failure to lower blood pressure may increase the risk of cardiovascular and cerebrovascular diseases, which should be highly valued. Through comprehensive management, including medication, lifestyle adjustments, and necessary medical interventions, most patients can effectively control their blood pressure. It is recommended to regularly monitor blood pressure, communicate with doctors, adjust treatment plans in a timely manner, and ensure that blood pressure remains stable within a safe range.

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