The elevation of transaminase in hepatitis B virus carriers should be alert to hepatitis activity, drug-induced liver injury, fatty liver and other liver diseases. The elevation of transaminase usually reflects the damage of liver cells, which may be caused by the active replication of hepatitis B virus, bad living habits or other liver diseases. It is recommended to seek medical advice in time to clarify the causes and intervene. Mild elevation of transaminase may be caused by staying up late, drinking alcohol, or vigorous exercise. After adjusting daily routine, quitting alcohol, and avoiding overwork, the indicators may return to normal. In case of moderate elevation, it is necessary to check the DNA load of hepatitis B virus. If it exceeds the normal value, it indicates that the virus replication is active, and antiviral treatment may be required. When combining symptoms of upper right abdominal pain and fatigue, be alert to the active stage of hepatitis and complete ultrasound and liver fibrosis scans. Severe elevation accompanied by jaundice or coagulation abnormalities may progress to liver failure and require immediate hospitalization for treatment. Long term history of high transaminase combined with obesity or diabetes may be related to metabolic fatty liver disease.

In daily life, one should avoid using liver damaging drugs such as acetaminophen tablets, prohibit drinking alcoholic beverages, and limit high-fat diets such as animal organs. Monitor the liver function, two half pairs of hepatitis B and viral load every 3-6 months, and seek medical advice in case of anorexia or skin yellowing. Moderate supplementation of liver protective drugs such as silibinin capsules is recommended, but antiviral treatment such as entecavir tablets must be administered under the guidance of an infectious disease specialist. Maintaining regular aerobic exercise such as brisk walking and controlling body mass index within the range of 18.5-23.9 can help improve liver metabolism.
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