What is the effective antibody titer after HPV vaccine?

The antibody titer reaching a certain level after HPV vaccination can be considered effective, but the specific value varies depending on the vaccine type and individual differences. At present, there is no unified threshold, and clinical observation mainly relies on long-term follow-up to observe the preventive effect. There are differences in antibody levels induced by bivalent, quadrivalent, and nonavalent HPV vaccines. The antibody titers of bivalent vaccines against HPV16/18 are usually higher, while quadrivalent and nonavalent vaccines have relatively lower antibody responses to other types but still have protective effects. Studies have shown that antibody titers naturally decrease over time after vaccination, but immune memory responses can rapidly produce protective antibodies during infection. The existing detection methods include serological neutralization test and ELISA, and the results of different detection methods are not comparable. Antibody testing is not a routine clinical procedure, as the protective effect of vaccines relies more on cellular immunity. After vaccination, all doses should be completed and vaccinated at recommended intervals. maintaining a regular schedule and balanced diet can help maintain immune function. Avoid behaviors that may affect immunity, such as smoking and excessive alcohol consumption. If there is a low immune function, you can consult a doctor to see if additional monitoring is needed. Even if the antibody level test results are not high, it is still not recommended to receive a booster vaccine. Existing data shows that those who have completed the entire vaccination process do not need to worry about the protective effect.