What indicators should be considered in the gastroscopy pathology report

The gastroscopy pathology report mainly observes indicators such as the degree of gastric mucosal inflammation, grading of atrophic gastritis, intestinal metaplasia, dysplasia, and helicobacter pylori infection. These indicators help evaluate the nature of gastric lesions and provide a basis for subsequent treatment.

1. Gastric mucosal inflammation

The degree of gastric mucosal inflammation is divided into chronic non atrophic gastritis and chronic atrophic gastritis. The pathological report will describe the depth and activity of inflammatory cell infiltration. Mild inflammation is characterized by lymphocyte infiltration in the mucosal layer, while moderate to severe inflammation can involve the submucosal layer. The accompanying symptoms include upper abdominal pain and postprandial fullness. Treatment should be combined with acid suppressants such as omeprazole enteric coated tablets and mucosal protectants such as magnesium aluminum carbonate chewable tablets.

2. Atrophic gastritis

The grading of atrophic gastritis is based on the degree of reduction of gastric glands, and is divided into no atrophy, mild, moderate, and severe. Pathologically, there is a decrease in main cells and parietal cells, as well as an increase in the epithelium of the gastric fovea. Severe atrophy may be accompanied by a decrease in gastric acid secretion, and regular monitoring of the pepsinogen ratio is necessary. Treatment can use Teprenone capsules to promote mucosal repair.

3. Intestinal metaplasia

Intestinal metaplasia is a precancerous lesion in which the gastric mucosa is replaced by intestinal type epithelium, and is divided into complete and incomplete types. Incomplete metaplasia is more closely related to the occurrence of gastric cancer, and pathology shows goblet cells and Paneth cells. It is recommended to have a gastroscopy review every 1-2 years and use folic acid tablets as an auxiliary intervention if necessary.

4. Heterogeneity

Heterogeneity is divided into low-grade and high-grade, with the latter belonging to the category of early cancer. Pathological features include enlarged cell nuclei, polarity disorder, and abnormal glandular structure. Low level lesions require 3-6 months of follow-up examination, while high-level lesions require endoscopic resection. After surgery, rehabilitation solution can be used to promote wound healing.

5. Positive detection of Helicobacter pylori in pathological sections of Helicobacter pylori

indicates current infection, which needs to be confirmed by rapid urease test or breath test. Infection can lead to sustained progression of inflammation, and the standard treatment regimen includes bismuth quadruple therapy, such as bismuth potassium citrate granules combined with antibiotics. After receiving the gastroscopy pathology report, one should avoid consuming high salt and pickled foods, quit smoking and limit alcohol consumption. Patients with Helicobacter pylori infection need serving of individual dishes, and family members suggest simultaneous detection. If there are warning symptoms such as weight loss and black stool during regular follow-up, timely follow-up gastroscopy is necessary. Daily supplementation of vitamin C and selenium can help with gastric mucosal repair.