What does low MCV mean in screening for thalassemia

Low MCV in screening for thalassemia usually suggests the possibility of thalassemia. MCV stands for mean red blood cell volume. A lower MCV indicates a smaller red blood cell volume, which may be related to factors such as iron deficiency anemia and thalassemia. Mediterranean anemia is a hereditary hemolytic anemia characterized by insufficient hemoglobin synthesis and small red blood cell volume due to defects in the globin gene. Low MCV in screening for thalassemia requires further diagnosis through hemoglobin electrophoresis, genetic testing, and other methods. Iron deficiency anemia can also lead to a decrease in MCV, but iron metabolism index testing can help differentiate it. Patients with thalassemia may present with symptoms such as pale complexion, fatigue, and delayed growth and development. Severe patients may also have symptoms such as hepatosplenomegaly and skeletal deformities. Mild thalassemia usually does not require special treatment, and attention should be paid to avoiding infection and overwork. Intermediate patients may require intermittent blood transfusions, while severe patients require regular blood transfusions and iron removal therapy. Patients diagnosed with thalassemia should avoid using oxidative drugs, and female patients should undergo genetic counseling before pregnancy. Moderate intake of folate rich foods such as green leafy vegetables and animal liver can help improve anemia symptoms in daily diet.

It is recommended that individuals with low MCV seek timely medical attention at the hematology department and complete relevant examinations to clarify the diagnosis. Pay attention to a balanced diet in daily life, avoid vigorous exercise, and regularly monitor changes in blood routine indicators. Confirmed patients should follow medical advice for standardized treatment, and couples of childbearing age should undergo prenatal screening and genetic counseling.