A positive HPV test during a physical examination usually indicates human papillomavirus infection, which can usually be cleared on its own in most cases, and a few cases of persistent infection may cause cervical lesions. HPV infection is mainly transmitted through sexual contact and may also be transmitted through indirect contact. It is recommended to have regular check ups and follow medical advice for intervention. HPV positivity is divided into high-risk and low-risk infections. Low risk types such as HPV6 and HPV11 may cause genital warts, manifested as perineal growths, which can be removed through laser or cryotherapy. High risk types such as HPV16 and 18 are closely related to cervical cancer and require vaginal colposcopy biopsy to determine the extent of the lesion. Persistent infection with high-risk HPV may lead to cervical intraepithelial neoplasia of grades 1-3, ultimately developing into invasive cancer. Early cervical lesions have no special symptoms, and some patients may experience contact bleeding or abnormal secretions. Cervical cancer screening uses TCT combined with HPV testing. Women aged 21-29 are recommended to undergo TCT testing every 3 years, while women aged 30 and above are recommended to undergo combined screening every 5 years. There is a high probability that HPV infection will turn negative on its own within 8-24 months after infection, and the immune system can clear the virus. Factors such as low immune function, long-term use of immunosuppressants, and multiple sexual partners may increase the risk of persistent infection. Interferon suppositories, Baofukang suppositories, and other drugs are commonly used as adjunctive treatments in clinical practice, but there are currently no specific anti HPV drugs available. The preventive HPV vaccine can cover people aged 9-45, the bivalent vaccine prevents HPV16 and 18, the quadrivalent vaccine increases protection against HPV6 and 11, and the nonavalent vaccine covers a wider range of types. Regular screening is still necessary after vaccination, as vaccines cannot eliminate existing infections. Maintaining a regular daily routine can help enhance immunity and promote virus clearance, while avoiding smoking can reduce the risk of cervical lesions. Using condoms during sexual intercourse can reduce cross infection, but it cannot completely block the transmission of HPV. Discovering HPV positivity does not require excessive anxiety, but regular follow-up should be taken seriously. If abnormal bleeding occurs, timely medical attention should be sought. Women over 30 years old are recommended to undergo HPV testing with their spouses, and those who test positive should be monitored together. Pay attention to perineal hygiene in daily life, avoid sitting in public baths, and disinfect and dry underwear at high temperatures.



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