A physical examination reveals splenomegaly, which usually requires a liver function test. Splenomegaly may be related to liver disease, and liver function tests can help evaluate liver health status. Common liver function tests include alanine aminotransferase, aspartate aminotransferase, total bilirubin, direct bilirubin, indirect bilirubin, total protein, albumin, globulin and other indicators. These indicators can reflect the degree of liver cell damage, bile excretion function, and protein synthesis ability. When splenomegaly is combined with abnormal liver function, it is necessary to consider the possibility of viral hepatitis, cirrhosis, portal hypertension and other diseases. Some blood system diseases may also lead to splenomegaly, but it is usually accompanied by abnormal blood routine indicators. Imaging examinations such as abdominal ultrasound or CT can help determine changes in spleen size and structure. For patients with mild splenomegaly and normal liver function, regular follow-up examinations can be conducted to observe changes.

It is recommended that patients with splenomegaly avoid vigorous exercise to prevent spleen rupture, have a light and easily digestible diet, and limit the intake of high-fat foods. Maintain a regular daily routine, quit smoking and limit alcohol consumption, and regularly check spleen size and liver function indicators. If symptoms such as abdominal pain, fatigue, and skin discoloration occur, seek medical attention promptly.
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