Should I take hepatoprotective drugs for high indirect bilirubin?

Whether the elevation of indirect bilirubin requires the use of hepatoprotective drugs should be determined based on the specific cause. In most cases, immediate use of hepatoprotective drugs is not necessary, and in rare cases, treatment should be targeted at the primary disease. Indirect bilirubin elevation is common in non liver direct injuries such as hemolytic diseases and genetic bilirubin metabolism disorders. Hemolytic anemia may lead to increased destruction of red blood cells and excessive indirect bilirubin production. In this case, priority should be given to treating the cause of hemolysis rather than using hepatoprotective drugs. Genetic metabolic diseases such as Gilbert syndrome usually only require observation and do not require special drug intervention. Some newborns with physiological jaundice may also show an increase in indirect bilirubin, which can mostly resolve on its own. When indirect bilirubin elevation is combined with liver cell damage, such as mixed hyperbilirubinemia caused by viral hepatitis or drug-induced liver damage, it may be necessary to use hepatoprotective drugs under the guidance of a doctor. Critical situations such as bilirubin encephalopathy caused by severe hemolysis require urgent treatment of the underlying disease and monitoring of liver function. Long term cholestatic liver disease with secondary indirect bilirubin elevation requires comprehensive evaluation to develop a treatment plan.

It is recommended to regularly monitor changes in liver function indicators and avoid self medication for liver protection. Maintain a regular schedule and balanced diet, and limit the intake of high-fat foods. If accompanied by symptoms such as yellowing of the skin and darkening of urine color, seek medical attention promptly to determine the cause. Individuals with abnormal liver function should strictly follow medical advice when taking medication and avoid using drugs or health supplements that increase the metabolic burden on the liver.