Should I stop taking medication for high transaminase levels caused by medication

Whether to stop taking medication due to elevated transaminase levels caused by medication depends on the specific situation. If the transaminase is mildly elevated and there are no other discomforts, it is usually not necessary to stop the medication immediately; If the transaminase is significantly elevated or accompanied by symptoms such as fatigue and jaundice, it is recommended to seek medical attention promptly and adjust the medication plan. Drug induced liver injury is a common cause of elevated transaminase levels, and some drugs such as statins, anti tuberculosis drugs, antipyretic analgesics, etc. may affect liver function. Mild elevation of transaminase may be a temporary reaction, and doctors may recommend continuing medication and regularly monitoring liver function, while also cooperating with liver protection treatment. It is necessary to avoid behaviors that increase the burden on the liver, such as alcohol consumption and high-fat diet, in daily life. When the transaminase exceeds the normal value by more than 3 times or symptoms such as skin and sclera jaundice, nausea and vomiting occur, it indicates severe liver damage and requires immediate cessation of suspected medication and professional treatment. Doctors may prescribe liver protective drugs such as reduced glutathione injection and polyene phosphatidylcholine capsules, and in severe cases, hospitalization is required. Patients with a history of liver disease or those who have used multiple medications in combination should be more cautious.

Patients should not stop or change medication on their own, and their medication history and symptom changes should be recorded. Detailed information should be provided when seeking medical attention. After adjusting the medication plan, it is recommended to recheck liver function every 1-2 weeks until the indicators are stable, and regular follow-up is still necessary in the later stage. Keep a light diet, supplement high-quality protein and vitamins in an appropriate amount, and avoid using health products or traditional Chinese patent medicines and simple preparations without doctor's guidance.