Should I stop taking medication for high transaminase levels?

Whether to stop taking medication due to elevated transaminase levels caused by medication depends on the specific situation. If the transaminase is mildly elevated and there are no other discomforts, medication can be continued and monitored under the guidance of a doctor; If the elevation is significant or accompanied by symptoms such as fatigue and jaundice, it is usually necessary to stop taking the medication immediately and seek medical attention. Elevated transaminase levels may be related to factors such as drug hepatotoxicity and individual metabolic differences. Some medications such as antibiotics, anti tuberculosis drugs, statins, etc. may cause mild elevation of transaminases. In this case, doctors may recommend continuing medication and strengthening liver function monitoring, while also cooperating with liver protection treatment. Patients should avoid behaviors that increase the burden on the liver, such as drinking alcohol and staying up late, and supplement high-quality protein and vitamins appropriately to promote liver cell repair. In most cases, transaminase levels gradually return to normal 1-2 weeks after discontinuation of medication. When the transaminase exceeds the normal value by more than 3 times, or there are obvious liver damage symptoms such as skin and sclera yellowing, nausea and vomiting, and abdominal distension, suspicious drugs should be stopped immediately. Doctors will prescribe liver protective drugs such as reduced glutathione injection and polyene phosphatidylcholine capsules based on the condition. Severe cases may require hospitalization for blood purification treatment. Long term use of high-risk drugs such as antiepileptic drugs and immunosuppressants should result in regular liver function check ups.

It is recommended that patients maintain a light diet during medication, avoid high-fat and high sugar foods, and drink no less than 1500 milliliters of water per day. If abnormalities such as darkening of urine color and itching of the skin are found, it is necessary to seek medical attention and have liver function rechecked in a timely manner. Without the permission of a doctor, it is not allowed to adjust the dosage of medication or stop taking medication on one's own, in order to avoid affecting the treatment of existing diseases.