Should HPV vaccination be administered if antibody test is negative after vaccination

After HPV vaccination, if the antibody test is negative, there is generally no need for vaccination. The HPV vaccine prevents human papillomavirus infection by stimulating the body to produce an immune response, but a negative antibody test does not necessarily mean immune protection is lost. The HPV vaccine currently used in clinical practice has long-term protective effects, and antibody levels may gradually decrease over time, but immune memory cells can still provide effective defense. The protective efficacy after vaccination is mainly verified through large-scale clinical trials, rather than relying on individual antibody test results. The World Health Organization and most national guidelines do not recommend routine HPV antibody testing, let alone recommending vaccination due to negative results. If there are special circumstances such as immune dysfunction, it is recommended to consult a professional doctor for evaluation. After receiving the HPV vaccine, it is recommended to maintain a healthy lifestyle, follow a regular schedule, have a balanced diet, exercise moderately, and avoid bad habits such as smoking and alcohol abuse. Regular cervical cancer screening is still necessary, even if vaccination has been completed. If you have doubts about the effectiveness of the vaccine, you can consult a professional medical institution to avoid blind vaccination. Maintaining good personal hygiene habits and avoiding high-risk sexual behavior can help further reduce the risk of HPV infection.