Reasons for abnormal liver function during onboarding physical examination

Abnormal liver function during the onboarding physical examination may be caused by factors such as fatty liver, viral hepatitis, drug-induced liver injury, alcoholic liver disease, autoimmune liver disease, etc. Abnormal liver function usually manifests as symptoms such as fatigue, decreased appetite, jaundice, etc. Further examination is needed to determine the cause.

1. Fatty liver

Long term high-fat diet, obesity and other factors may lead to the accumulation of fat in liver cells, causing fatty liver. Mild fatty liver may have no obvious symptoms, while moderate to severe cases may present with hidden pain and fatigue in the upper right abdomen. Treatment requires adjusting dietary structure, reducing high-fat food intake, and increasing aerobic exercise. If combined with metabolic syndrome, liver protective drugs such as silibinin capsules and polyene phosphatidylcholine capsules can be used according to medical advice.

2. Viral hepatitis

Hepatitis B virus or hepatitis C virus infection is a common cause, which may be transmitted through blood or body fluids. During the acute phase, symptoms such as fever, nausea, and skin discoloration may occur, while chronic infections may progress to cirrhosis. Diagnosis requires testing for hepatitis virus markers, and treatment includes antiviral drugs such as entecavir tablets, sofosbuvir, vipatasvir tablets, while avoiding alcohol consumption and hepatotoxic drugs.

3. Drug induced liver injury

Some antibiotics, antipyretic analgesics, Chinese herbal medicines, etc. may cause liver cell damage, manifested as elevated transaminase levels. Common symptoms include itching of the skin, darkening of urine color, and in severe cases, coagulation dysfunction may occur. Suspected drugs should be stopped immediately, and compound glycyrrhizin tablets, glutathione tablets, and other drugs should be used according to medical advice to promote liver cell repair.

4. Alcoholic liver disease

Long term excessive alcohol consumption can lead to hepatic steatosis, inflammation, and even fibrosis. In the early stages, it may only manifest as an increase in gamma glutamyl transpeptidase, and in the later stages, liver pain and ascites may occur. The key to treatment lies in strict abstinence from alcohol, supplementation of B vitamins, and the use of medications such as Metadoxine capsules as adjuvant therapy for critically ill patients.

5. Autoimmune liver disease

Abnormal immune system attack on liver tissue may lead to diseases such as primary biliary cholangitis, which is common in middle-aged women. Symptoms include itching of the skin, dry mouth and eyes, and laboratory tests showing positive anti mitochondrial antibodies. The treatment requires the use of ursodeoxycholic acid capsules combined with budesonide capsules to regulate immunity, and regular monitoring of liver function changes. After discovering abnormal liver function, one should avoid staying up late, drinking alcohol, and consuming high-fat diets, and supplement high-quality protein such as fish and soy products in moderation. It is recommended to have liver function and liver ultrasound rechecks every 3-6 months. If there is continuous worsening of fatigue, abdominal distension, or skin discoloration, it is necessary to seek medical attention promptly at the gastroenterology or liver disease department. Daily consumption of substitute tea drinks such as chrysanthemum and cassia seed tea, which have liver protective effects, cannot replace regular treatment.