Is there a significant relationship between HPV18 positivity and cervical cancer?

HPV18 positivity is closely related to cervical cancer and belongs to high-risk HPV infection. HPV18 positivity may be caused by factors such as sexual contact transmission, weakened immunity, and multiple sexual partners. It can be diagnosed through cervical TCT examination, HPV-DNA testing, vaginal colposcopy examination, and other methods. It is recommended to seek medical attention promptly and receive standardized treatment and regular follow-up under the guidance of a doctor.

1. High risk HPV

HPV18 belongs to the high-risk human papillomavirus, and persistent infection may cause cervical intraepithelial neoplasia. High risk HPV causes cancer by integrating host cell DNA, and clinical manifestations include contact bleeding, abnormal vaginal discharge, and other symptoms. After diagnosis, antiviral treatment can be carried out under the guidance of a doctor using drugs such as interferon suppositories, Baofukang suppositories, recombinant human interferon alpha-2b vaginal effervescent tablets, etc.

2. The probability of HPV 18 positive developing into cervical cancer is significantly higher than that of the general population, but not all infected individuals will develop cancer. The process of carcinogenesis usually takes 5-10 years, during which symptoms such as increased vaginal discharge and menstrual abnormalities may occur. Regular cervical cancer screening can effectively detect precancerous lesions, and it is recommended to undergo a TCT test combined with HPV testing every 3 years.

3. Transmission route

HPV18 is mainly transmitted through sexual contact, but can also be transmitted vertically from mother to child or through contact with contaminated materials. Using condoms can reduce the risk of transmission, but cannot completely block it. Infected individuals should avoid having multiple sexual partners, and sexual partners should also undergo HPV testing and receive HPV vaccination if necessary for prevention.

4. Immune clearance

Some HPV18 positive cases can be cleared through self immunity, and the clearance time is usually 6-24 months. Improving immunity can help the virus turn negative. It is recommended to maintain a regular schedule, balanced diet, and appropriate exercise. Immunomodulators such as thymosin enteric coated tablets and pidotimod granules can be used in clinical practice, but they must be used under the guidance of a doctor.

5. Preventive measures

Vaccination with the nine valent HPV vaccine can prevent HPV18 infection, and the optimal age for vaccination is 9-45 years old. Even if infected with HPV18, vaccination can still prevent other high-risk infections. Daily attention should be paid to keeping the external genitalia clean, avoiding unclean sexual behavior, quitting smoking and limiting alcohol consumption, and reducing the risk of cervical cancer. HPV18 positive patients should establish a health record and undergo regular follow-up, with HPV and TCT rechecks every 6-12 months. Eat more foods rich in vitamins A, C, and E, such as carrots, kiwifruit, nuts, etc., and avoid spicy and stimulating foods. Maintain moderate exercise such as yoga, brisk walking, etc., ensure sufficient sleep, and avoid overexertion. When abnormal vaginal bleeding or discharge occurs, seek medical attention immediately and do not self medicate to delay the condition.