Whether the elevated lymphocyte count in children's blood routine is normal needs to be analyzed based on specific circumstances. If it is a temporary increase during the recovery period of viral infection or after vaccination, it usually belongs to physiological reactions; If the continuous abnormal elevation is accompanied by symptoms such as fever and lymph node enlargement, it may be related to pathological factors such as infectious mononucleosis and acute lymphoblastic leukemia.

Viral infection is a common cause of increased lymphocyte count in children. After infection with respiratory syncytial virus, adenovirus, etc., lymphocyte reactivity increases, manifested as mild elevation without other abnormal indicators. This type of situation usually does not require special treatment and can recover on its own within 1-2 weeks after infection control. After vaccination, there may also be a temporary increase in the proportion of lymphocytes, which is a normal immune response process. Pathological lymphocytosis requires vigilance against hematological diseases. In children with infectious mononucleosis, in addition to an increase in absolute lymphocyte count, atypical lymphocytes can be seen on peripheral blood smears, accompanied by symptoms such as pharyngitis and hepatosplenomegaly. Acute lymphoblastic leukemia can result in a significant increase in lymphocyte proportion accompanied by anemia and thrombocytopenia, and can be diagnosed by bone marrow aspiration. Chronic active EB virus infection and other rare diseases can also lead to persistent lymphocytosis.

It is recommended that parents make a comprehensive judgment based on the child's clinical manifestations when discovering abnormal blood routine. Patients with mild increase in the proportion of lymphocytes and no other symptoms can undergo regular follow-up examinations. If there are persistent abnormalities or accompanied by symptoms such as fever and bleeding tendency, it is necessary to seek medical attention promptly at the pediatrics or hematology department, and further evaluate with peripheral blood smear, EB virus antibody, bone marrow examination, etc.

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