Is it important to have ascites in ovarian cancer with negative ultrasound?

Ovarian cancer patients with ascites detected by ultrasound examination usually require high attention, which may be related to tumor progression or complications. When ovarian cancer is combined with ascites, the mechanism of ascites production is mainly related to the increased capillary permeability caused by peritoneal dissemination of tumor cells. Tumor cells stimulate peritoneal mesothelial cells to secrete excessive fluid, while lymphatic reflux obstruction can also exacerbate ascites formation. A large amount of ascites may compress the diaphragm and affect respiratory function, leading to symptoms such as bloating and decreased appetite. A small amount of ascites may only present as mild abdominal discomfort, but all indicate that the disease is in an active phase. Ascites are often bloody or serous in nature, and cytological examination may reveal cancer cells. The amount of ascites is often positively correlated with tumor burden, but in some cases, there may be a small amount of ascites accompanied by extensive metastasis.

Daily attention should be paid to recording changes in abdominal circumference to avoid aggravating discomfort with vigorous exercise. It is advisable to choose high protein and easily digestible foods for diet, and to reduce bloating with small and frequent meals. Maintain moderate activity to promote intestinal peristalsis, but immediately rest in bed when breathing difficulties occur. Regularly monitor changes in ascites using ultrasound and strictly follow medical advice for anti-tumor treatment. Pay attention to observing urine output and lower limb edema, and seek medical attention promptly if any abnormalities are found.