A high transaminase level in children's physical examination may be related to obesity, but it may also be caused by other factors. Elevated transaminase levels usually reflect abnormal liver function, and common causes include obesity related fatty liver, viral infections, drug damage, genetic metabolic diseases, or biliary problems. It is recommended that parents take their children to seek medical attention in a timely manner to investigate the specific cause. Obesity is one of the common causes of elevated transaminase levels in children. Long term high calorie diet and lack of exercise may lead to fat accumulation in the liver, forming non-alcoholic fatty liver disease. In this case, mild elevation of transaminase is usually accompanied by symptoms such as overweight and increased waist circumference. By adjusting the diet structure, increasing aerobic exercise, and controlling weight gain, the liver function of most children can gradually improve. In addition to obesity, viral hepatitis such as hepatitis B or C infection can also lead to abnormal transaminase levels. These children may experience symptoms such as fatigue, decreased appetite, and nausea. Some genetic metabolic diseases, such as Wilson's disease and glycogen storage disorder, may only manifest as elevated transaminase levels in the early stages. Long term use of antibiotics, antiepileptic drugs, or exposure to toxic substances may also damage liver cells. Biliary system diseases such as biliary atresia and cholangitis may also be accompanied by fluctuations in transaminase levels. When parents discover that their children have high transaminase levels, they should record their child's recent diet, medication, and physical changes, and cooperate with doctors to complete further examinations such as hepatitis virus screening, liver ultrasound, and metabolic disease testing. In daily life, it is necessary to avoid giving children high sugar and high-fat snacks, ensure more than 60 minutes of moderate to high-intensity exercise per day, and regularly monitor weight and liver function indicators. If diagnosed with obesity related liver injury, a scientific weight loss plan should be developed under the guidance of a nutritionist.



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