Is hepatitis B Two Pairs and Half Big Three Yang Infectious

Two pairs and half of hepatitis B and three positive are highly infectious, belonging to the highly infectious hepatitis B virus infection state. Big three positive means that hepatitis B B surface antigen, hepatitis B B e antigen and hepatitis B core antibody are positive at the same time, indicating that the virus replication is active, and there is a high concentration of hepatitis B virus in the blood and body fluid.

Two and a half pairs of patients with hepatitis B and big three positives usually have high viral load, active virus replication, and are significantly more infectious than small three positives or other hepatitis B virus infections. The transmission routes include vertical transmission from mother to child, blood transmission, and sexual contact transmission. Daily close contact with items that may come into contact with blood, such as shared toothbrushes and razors, also poses a risk of transmission. Hepatitis B virus can survive for a long time in the external environment, has a certain resistance to disinfectants, and increases the transmission probability. Even without obvious symptoms, patients with triple positive may still transmit the virus to others through the above-mentioned channels. In rare cases, the infectivity of patients with triple positive may be relatively low, mainly due to viral mutations leading to a decrease in e-antigen expression, or temporary reduction in viral load during the immune clearance period. But this situation is relatively rare and cannot be used as a basis for judging infectivity. After antiviral treatment, some patients may still maintain a high level of three positive, but their viral load has dropped below the detection limit, and their infectivity will significantly decrease.

It is recommended that two and a half pairs of patients with hepatitis B and three positives should regularly monitor liver function, hepatitis B virus DNA load and liver ultrasound. Family members should be vaccinated against hepatitis B and avoid sharing personal items that may contact blood. Patients should avoid drinking alcohol, maintain a regular schedule, and follow medical advice for antiviral treatment. Medical personnel should take standard precautions when coming into contact with patients' blood and body fluids. Newborns should be vaccinated with hepatitis B vaccine and hepatitis B immunoglobulin in time after birth to block mother to child transmission.