How to check hepatitis B antibody

The physical examination of hepatitis B antibody can be carried out through the five tests of hepatitis B, the quantitative test of hepatitis B surface antibody, and the test of hepatitis B core antibody. Hepatitis B antibody test is usually used to evaluate the vaccination effect or previous infection.

1. Five tests for hepatitis B B

The five tests for hepatitis B B are routine methods for screening hepatitis B B virus infection and immune status, including five indicators of hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B e antigen, hepatitis B e antibody and hepatitis B core antibody. Positive hepatitis B surface antibody indicates the existence of protective antibody, which may be produced by successful vaccination or recovery of previous infection. The test requires fasting venous blood sampling, and the results can reflect the current infection status and immune level.

2. Quantitative detection of hepatitis B surface antibody

Quantitative detection of hepatitis B surface antibody can accurately measure the antibody concentration and judge the intensity of immune protection. Antibody titers exceeding 10mIU/ml are considered protective, and those below this value may require vaccination. This test is suitable for evaluating the effectiveness of vaccination or monitoring the immunity of high-risk populations, and needs to be completed through techniques such as chemiluminescence.

3. Detection of hepatitis B core antibody

Detection of hepatitis B core antibody is mainly used to distinguish past infection from current infection. Positive core antibody IgM indicates recent infection, while positive IgG often indicates previous infection. This test needs to be combined with other indicators for comprehensive judgment. The positive core antibody alone cannot determine the immune status, and further inspection of hepatitis B surface antigen and surface antibody is required.

4. Quick test strip

hepatitis B antibody quick test strip can be used for preliminary screening, and the results can be obtained through fingertip blood in 15 minutes. However, this method has low sensitivity and may result in false negatives, making it only suitable for emergency screening. The formal physical examination is recommended to be based on laboratory testing in the hospital. If the test strip results are abnormal, further serological confirmation is required.

5. Chemiluminescence detection

Chemiluminescence detection is the most accurate hepatitis B antibody detection technology at present. It can detect low concentration antibodies, and its sensitivity exceeds that of ELISA. Suitable for evaluating individuals with low immune function or those with weak reactions after vaccination, it can identify trace antibodies that may have been missed by traditional methods, but the detection cost is relatively high.

It is recommended to maintain a normal daily routine before testing and avoid vigorous exercise that may affect the results. If the antibody is negative or the titer is insufficient, consult the doctor to reseed the hepatitis B vaccine. High risk behaviors such as sharing syringes and unprotected sex should be avoided in daily life. Medical personnel and other occupational exposure risk individuals should regularly check their antibody levels. Pay attention to balanced nutrition in diet, and supplement high-quality protein and vitamins appropriately to help maintain immune function.