It is generally recommended to have a physical examination 1-2 weeks after receiving the HPV vaccine. The timing of the physical examination should be comprehensively judged based on the type of vaccine, individual physical condition, and examination items. Early physical examination may affect the accuracy of some indicators. Within one week after receiving the HPV vaccine, the body is in the immune response stage and may experience temporary fever, redness and swelling at the injection site, and other reactions. At this time, blood routine, inflammatory markers and other tests may show a mild increase in white blood cell count or abnormal C-reactive protein, which may interfere with the judgment of physical examination results. If the physical examination includes cervical TCT or HPV virus screening, vaccine induced antibodies may not have fully formed, and the test results may not reflect the true immune effect. After 2 weeks of vaccination, the immune response of most people tends to stabilize, and antibody levels gradually increase. At this time, physical examination data is more informative. For biochemical tests that require fasting blood draw, it is recommended to avoid within 3 days after vaccination, as some individuals may experience mild gastrointestinal reactions. After vaccination, the injection site should be kept clean and dry, and vigorous exercise should be avoided for 24 hours. Three days before the physical examination, pay attention to a light diet and avoid drinking alcohol or high-fat foods that may affect liver function and other indicators. If there is persistent high fever or severe allergic reaction after vaccination, medical attention should be sought promptly instead of prioritizing physical examination. After completing all HPV vaccine doses, regular cervical cancer screening can be conducted to comprehensively evaluate the protective effect.

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