Does fatty liver lead to elevated blood lipids?

Fatty liver may lead to elevated blood lipids. Fatty liver and dyslipidemia often coexist and interact with each other. Patients with fatty liver have impaired liver metabolic function, which may lead to increased synthesis and decreased breakdown of triglycerides, resulting in elevated blood lipids. The liver is an important organ for lipid metabolism. When the fat accumulation in liver cells exceeds 5%, it affects the synthesis and secretion of very low-density lipoprotein, leading to an increase in triglyceride levels in the blood. Meanwhile, patients with fatty liver often have insulin resistance, which promotes the release of free fatty acids and further exacerbates blood lipid abnormalities. Some patients with moderate fatty liver may experience a decrease in high-density lipoprotein cholesterol and an increase in low-density lipoprotein cholesterol. Severe fatty liver patients have more pronounced blood lipid abnormalities, which may manifest as mixed hyperlipidemia.

It is recommended that patients with fatty liver regularly monitor their blood lipid levels and improve liver metabolic function through low-fat diet, weight control, moderate exercise, and other methods. Limit the intake of saturated fatty acids and trans fatty acids, and increase the intake of dietary fiber and high-quality protein. Avoid drinking alcohol and abusing drugs, and regularly check liver function when using lipid-lowering drugs according to medical advice. Patients with combined obesity and fatty liver can significantly improve liver steatosis and dyslipidemia by reducing their weight by 5-10%.

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