Can TCT low-grade lesions become cancerous

Low degree TCT lesions have the possibility of carcinogenesis, but the probability is low. Low degree lesions usually refer to grade 1 cervical intraepithelial neoplasia, most of which can self resolve or remain stable, with only a few possibly progressing to high-grade lesions or cervical cancer. Persistent infection with high-risk HPV is the main risk factor. About 60% of patients with low-grade lesions can clear the virus through their own immune system within 1-2 years, and the lesions will naturally disappear. 30% may maintain a low-grade lesion state for a long time, and only 10% may progress to a high-grade lesion. This process usually takes 5-10 years, and regular follow-up can detect abnormal changes in a timely manner. Vaginal examination and HPV typing testing can more accurately assess risk. When combined with high-risk HPV persistent infection, immune dysfunction, smoking, etc., the risk of cancer is relatively increased. If symptoms such as contact bleeding and abnormal secretions occur, or if the lesion is found to have escalated during follow-up, timely treatment such as cervical conization should be performed. LEEP knife surgery and cryotherapy are commonly used intervention methods.

It is recommended to undergo TCT combined with HPV testing every 6-12 months to avoid smoking and having multiple sexual partners. Maintaining a regular daily routine can help enhance immunity, and sulforaphane found in cruciferous vegetables such as broccoli may help clear HPV infections. If any abnormalities are found, they should be promptly evaluated at the gynecology clinic.