Can neurosyphilis be transmitted? Husband, both are negative

neurosyphilis is generally not transmitted through daily contact, and a negative test result for both partners usually indicates no risk of transmission. The main transmission routes of neurosyphilis include mother to child vertical transmission, sexual contact transmission, blood transmission, and in rare cases, it may be transmitted through shared syringes or medical devices.

Neurosyphilis is a chronic infection caused by Treponema pallidum invading the central nervous system, and its infectivity depends on the disease stage and the presence of active skin lesions. Patients with primary and secondary syphilis have higher infectivity when there are ulcers or rashes on the skin and mucous membranes, while patients with advanced neurosyphilis usually have no skin lesions, and the probability of transmission through sexual contact is extremely low at this time. The negative test results of both husband and wife indicate that no Treponema pallidum has been detected in their bodies, and daily cohabitation will not cause transmission.

In special circumstances, false negatives may need to be considered, such as window period testing or serum fixation phenomena. The window period may result in false negative test results due to the lack of antibody production, which poses a potential risk of infection. Although patients with fixed serum are not contagious, regular follow-up is necessary to ensure stable antibody titers. If there is high-risk contact or suspected exposure, it is recommended to undergo relevant testing at regular intervals. After being diagnosed with neurosyphilis, standardized treatment and regular follow-up should be carried out, and penicillin drugs are the preferred treatment option. It is necessary to avoid unsafe sexual behavior in daily life, and joint testing by both spouses can effectively block the transmission chain. Maintaining a healthy lifestyle can help improve immunity. During treatment, pay attention to balanced nutrition and moderate exercise to avoid excessive fatigue affecting the recovery process. If neurological symptoms such as headache and visual abnormalities occur, seek medical attention promptly for follow-up examination.