Can Helicobacter pylori positivity lead to gastroesophageal reflux

helicobacter pylori positivity may be related to gastroesophageal reflux, but it is not a direct pathogenic factor. Helicobacter pylori infection mainly causes diseases such as gastritis and gastric ulcers, and whether it leads to gastroesophageal reflux needs to be judged based on individual differences. Helicobacter pylori infection may affect gastroesophageal reflux by altering gastric acid secretion. Some patients experience reduced gastric acid secretion and reduced reflux symptoms after infection; A small number of patients may experience reflux due to worsening gastric mucosal inflammation. The toxin produced by Helicobacter pylori can damage the gastric mucosal barrier and indirectly affect the function of the lower esophageal sphincter. Long term untreated infection may worsen gastric lesions and increase the probability of reflux. The occurrence of gastroesophageal reflux is also related to factors such as obesity, diet, and pregnancy. After eradicating Helicobacter pylori, some patients may experience worsening reflux symptoms, which is related to the recovery of gastric acid secretion. When gastroesophageal reflux disease is combined with Helicobacter pylori infection, it is necessary to evaluate the causal relationship between infection and reflux. Patients with positive Helicobacter pylori who experience reflux symptoms should undergo comprehensive gastroscopy to determine the degree of esophageal injury. The association between gastroesophageal reflux and Helicobacter pylori infection is weak in special populations such as children and the elderly.

It is recommended that patients with Helicobacter pylori positive and gastroesophageal reflux symptoms seek timely treatment in the gastroenterology department, complete carbon-13 breath test and gastroscopy examination. Avoid high-fat diet and caffeine intake in daily life, and do not lie flat within 2 hours after eating. Personalized treatment plans should be developed based on the primary and secondary relationship between infection and reflux, and proton pump inhibitors and antibiotics can be used in combination.