Can abnormal coagulation function lead to slow wound healing?

Abnormal coagulation function usually leads to slower wound healing. Abnormal coagulation function may be caused by genetic hemophilia, vitamin K deficiency, liver cirrhosis, long-term use of anticoagulant drugs, and other factors, manifested as prolonged bleeding time, subcutaneous bruising, and other symptoms. When coagulation function is abnormal, the body finds it difficult to quickly form a stable blood clot to seal the wound. A decrease in platelet count or functional defects can affect initial hemostasis, while a lack of coagulation factors hinders the formation of a fibrin network, leading to continuous bleeding or recurrent bleeding in the wound. In this case, the inflammatory response period is prolonged, fibroblast migration and collagen deposition are obstructed, and neovascularization is delayed, thereby slowing down the healing process. Commonly seen in hemophilia patients with mild trauma and difficulty in absorbing joint cavity blood, or in patients with liver cirrhosis with persistent bleeding from surgical incisions.

Some special circumstances may not affect the healing speed. If the degree of coagulation dysfunction is relatively mild, such as mild vitamin K deficiency, which can still form effective hemostasis through local compression, or some genetic coagulation factor deficiencies only manifested as abnormal laboratory indicators without clinical bleeding tendency, the wound healing time may be no different from that of ordinary people. But such situations need to be strictly monitored to avoid complications such as secondary infections.

Patients with coagulation dysfunction should prolong the compression hemostasis time after injury, and seek medical attention promptly to supplement the missing coagulation factors if necessary. Avoid vigorous exercise and external injuries in daily life, regularly monitor coagulation indicators, and consume foods rich in vitamin K such as broccoli and spinach in a balanced manner. Severe abnormalities require an assessment of bleeding risk and the development of alternative treatment plans before surgery.