What should I do if my thyroid stimulating hormone receptor antibody is high

Elevated levels of thyroid stimulating hormone receptor antibody TRAb usually indicate autoimmune thyroid disease, which can be intervened through drug therapy, radioactive iodine therapy, surgical intervention, regular monitoring, and lifestyle adjustments. Elevated TRAb is mainly related to autoimmune abnormalities such as Graves' disease and Hashimoto's thyroiditis.

1. Drug therapy:

Antithyroid drugs such as methimazole and propylthiouracil can inhibit thyroid hormone synthesis and are suitable for active Graves' disease. During medication, liver function and white blood cell count should be monitored, and some patients may experience adverse reactions such as rash or joint pain. Beta blockers such as propranolol can alleviate symptoms such as palpitations and hand tremors.

2. Radioiodine therapy:

reduces hormone secretion by destroying thyroid tissue and is suitable for patients with ineffective or recurrent medication. Thyroid volume and iodine uptake rate need to be evaluated before treatment, and temporary hypothyroidism may occur after treatment, requiring lifelong replacement therapy. Pregnant and lactating women are prohibited from using this method.

3. Surgical resection:

Subtotal thyroidectomy is suitable for patients with thyroid enlargement compressing the trachea or suspected malignant transformation. Preoperative medication is required to control thyroid function to normal range, and postoperative monitoring of blood calcium is necessary to prevent parathyroid damage. Surgical complications include vocal cord paralysis and permanent hypothyroidism.

4. Regular monitoring:

Recheck thyroid function and TRAb levels every 3-6 months to observe the trend of antibody titers. Pregnant women with continuous positive TRAb should monitor the thyroid status of their fetuses, and newborns should be screened for congenital hyperthyroidism after birth. Patients with eye protrusion symptoms need regular ophthalmic evaluations.

5. Lifestyle adjustment:

Avoid high iodine foods such as seaweed and limit caffeine intake to alleviate palpitations. Ensuring the intake of trace elements such as selenium and zinc helps regulate immunity, and regular sleep can improve one's own immune status. Individuals with combined eye diseases should quit smoking and wear anti glare glasses.

Patients with elevated TRAb should pay attention to changes in heart rate and weight in daily life. If there are abnormal symptoms of thyroid function such as fear of heat, excessive sweating, or coldness and fatigue, they should be re examined in a timely manner. It is recommended to choose non iodized salt cooking and consume fish and eggs rich in vitamin D in moderation. Engaging in low-intensity exercises such as Tai Chi and yoga every week can help stabilize autonomic nervous system function and prevent arrhythmia induced by intense exercise. Lack of sleep may exacerbate immune disorders, and it is recommended to maintain 7-8 hours of regular sleep. Psychological stress may affect antibody levels, and anxiety can be alleviated through mindfulness meditation.