What problem does low urea indicate

Low urea levels are usually caused by factors such as insufficient protein intake, abnormal liver function, physiological changes during pregnancy, diuretic use, or chronic wasting diseases. Urea is the end product of protein metabolism, and a decrease in its level may reflect abnormal metabolic status in the body.

1. Protein deficiency:

Long term low protein diet or malnutrition can lead to insufficient amino acid metabolism materials and reduced liver synthesis of urea. Vegetarians, dieting individuals, or patients with digestive and absorption disorders may experience this condition and need to improve it by increasing high protein foods such as eggs and fish.

2. Liver function damage:

Diseases such as cirrhosis and hepatitis can reduce the hepatic ornithine cycle function and affect urea synthesis. These patients often have symptoms such as elevated transaminase levels and jaundice, and need to be treated with liver protective drugs such as glutathione and silymarin in combination.

3. Physiological changes during pregnancy:

Increased blood volume in pregnant women leads to a decrease in urea nitrogen dilution, which is a normal physiological phenomenon. The urea value in the middle and late stages of pregnancy can be 30% lower than normal, and no special treatment is required, but the possibility of liver disease should be ruled out.

4. Drug factors:

Diuretics such as furosemide can accelerate urea excretion, and long-term use may lead to lower values. Some antibiotics, such as gentamicin, may also interfere with the test results, but they usually return to normal after discontinuation.

5. Chronic consumption:

Consumptive diseases such as malignant tumor and tuberculosis have increased protein catabolism and reduced urea production. These patients often suffer from emaciation and hypoalbuminemia, and require targeted treatment for the underlying disease.

It was found that low urea levels should be judged comprehensively based on other indicators. Patients with abnormal liver function should limit visceral intake and supplement with vitamin B family; People with protein deficiency can increase their daily intake of high-quality protein by 20-30g, such as 300ml of milk paired with 100g of chicken breast; Pregnant women and those caused by medication are recommended to have a follow-up examination after one month. When there is no long-term improvement or accompanied by symptoms such as fatigue and edema, further examinations such as liver function, kidney function, and tumor markers should be conducted.