What medicine should be taken for delusional delusions and delusions

Patients with delusional disorder can take antipsychotic drugs such as olanzapine, risperidone, quetiapine, aripiprazole, and clozapine according to medical advice. Delusions belong to the spectrum disorder of schizophrenia and require a combination of psychological therapy and medication intervention to control symptoms.

1. Olanzapine

Olanzapine is suitable for treating schizophrenia and related delusional symptoms by regulating dopamine and serotonin receptors to improve thinking disorders. Common adverse reactions include drowsiness and weight gain, and long-term use requires monitoring of blood glucose and lipid levels. This medicine has a good control effect on positive symptoms such as delusions, but may cause extrapyramidal reactions.

2. Risperidone

Risperidone can alleviate symptoms such as paranoid ideation and relational delusions in patients with delusions, and is a second-generation antipsychotic drug. Its mechanism of action is dopamine D2 receptor antagonism, which may cause sedentary behavior or elevated prolactin levels. Effective for both acute attacks and maintenance treatment, caution should be exercised when adjusting the dosage for elderly patients.

3. Quetiapine

Quetiapine has an improving effect on the emotional symptoms associated with delusions, with a wide receptor spectrum but significant sedative effects. Suitable for delusional patients with anxiety and depression, attention should be paid to the risk of orthostatic hypotension. The metabolic pathway of this drug is complex, and patients with abnormal liver function need to reduce their dosage.

4. Aripiprazole

Aripiprazole, as a dopamine partial agonist, has a regulatory effect on delusional symptoms and has fewer metabolic side effects. Suitable for young patients who require long-term medication, which may cause headaches or insomnia. The drug has a good effect on improving negative symptoms, but it needs to be gradually adjusted to the therapeutic dose.

5. Clozapine

Chlorpromazine is commonly used for the treatment of refractory delusions, and strict monitoring of the risk of granulocyte deficiency is required. Stubborn delusions that are ineffective with traditional drugs may be effective, but there is a risk of seizures and myocarditis. Before use, a baseline blood routine examination is required, and regular follow-up examinations are required during treatment. In addition to medication treatment, delusional patients should also cooperate with cognitive-behavioral therapy to correct misconceptions, and family members should participate in the rehabilitation process to create a supportive environment. Maintaining a regular schedule and moderate exercise can help improve symptoms and avoid consuming psychoactive substances such as alcohol. Regular follow-up visits are required to evaluate the efficacy and side effects, and medication adjustments must strictly follow medical advice. A balanced diet and social activities have a positive impact on functional recovery, and hospitalization is recommended during acute attacks to ensure medication safety.