It is usually recommended to identify the cause of elevated creatine kinase before targeted treatment. Commonly used drugs include coenzyme Q10, disodium adenosine triphosphate, vitamin E, etc. Elevated creatine kinase may be related to factors such as muscle injury, myocarditis, and hypothyroidism, and medication selection should be based on specific causes.
1. Coenzyme Q10:
Coenzyme Q10 is an important coenzyme for cellular energy metabolism, which can improve oxidative stress in myocardial cells and is suitable for creatine kinase elevation caused by myocardial injury. This drug can assist in relieving symptoms of myocardial ischemia, but it needs to be combined with etiological treatment. During medication, liver function should be monitored to avoid co administration with other cholesterol lowering drugs.
2. Adenosine triphosphate disodium:
Adenosine triphosphate disodium can directly provide energy to cells and promote the repair of damaged muscle tissue. The effect of elevated creatine kinase caused by excessive exercise or muscle strain is significant. Intravenous administration requires strict control of infusion rate, which may cause adverse reactions such as chest tightness. Patients with coronary heart disease should use it with caution.
3. Vitamin E:
Vitamin E, as an antioxidant, can alleviate lipid peroxidation damage to muscle cell membranes and is suitable for abnormal indicators caused by chronic muscle disease. Long term use should pay attention to dosage, as excessive use may lead to a tendency towards bleeding. When used in combination with anticoagulant drugs, the dosage needs to be adjusted.
4. Etiological and therapeutic drugs:
If caused by hypothyroidism, levothyroxine sodium should be supplemented; Patients with myocarditis may require glucocorticoids; Rhabdomyolysis requires intravenous fluid replacement and alkalization of urine. All medications must be used under the guidance of a doctor and the dosage cannot be adjusted by oneself.
5. Adjuvant therapeutic drugs:
Inosine tablets can promote energy metabolism and improve muscle microcirculation; Huangqi injection, a traditional Chinese medicine, has a protective effect on myocardial cells. When using combination therapy, it is important to pay attention to drug interactions and regularly review creatine kinase and liver and kidney function indicators. Patients with elevated creatine kinase levels should avoid vigorous exercise in their daily lives and ensure adequate rest. Increase the intake of high-quality protein in diet, such as fish and chicken breast, and supplement fruits rich in vitamin C, such as kiwi and oranges. Pay attention to monitoring the color of urine and seek medical attention immediately if soy sauce colored urine appears. During the recovery period, low-intensity aerobic exercise such as walking and swimming can be performed 3-4 times a week, with each session lasting no more than 30 minutes. Patients with hypertension or diabetes need to strictly control blood pressure and blood sugar, and regularly review myocardial enzymes and electrocardiogram. Pay attention to keeping warm in winter to prevent respiratory infections from causing myocardial damage.
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