What medication can be taken normally for low ejection fraction

A low ejection fraction usually indicates heart failure. Under the guidance of a doctor, angiotensin converting enzyme inhibitors such as perindopril tablets, beta blockers such as metoprolol extended release tablets, aldosterone receptor antagonists such as spironolactone tablets, angiotensin receptor enkephalinase inhibitors such as sacubitril valsartan sodium tablets, and sodium glucose cotransporter 2 inhibitors such as dapagliflozin tablets can be used to improve cardiac function. A decrease in ejection fraction is often associated with diseases such as myocardial infarction, myocarditis, and hypertensive heart disease, and requires comprehensive treatment based on the underlying causes.

1. Perindopril tablets

Perindopril tablets belong to angiotensin-converting enzyme inhibitors, which reduce the production of angiotensin II by inhibiting angiotensin-converting enzyme, lower cardiac afterload, and improve myocardial remodeling. The drug is suitable for patients with chronic heart failure, especially for patients with low ejection fraction combined with hypertension or diabetes. During medication, blood potassium and renal function should be monitored, and adverse reactions such as dry cough may occur.

2. Metoprolol Extended Release Tablets

Metoprolol Extended Release Tablets are selective beta 1 receptor blockers that improve cardiac function by slowing down heart rate and reducing myocardial oxygen consumption. Long term use can reverse ventricular remodeling and increase ejection fraction. The drug needs to be gradually increased from a small dose, and common adverse reactions include fatigue and bradycardia. It is contraindicated for patients with acute heart failure or severe bradycardia.

3. Spironolactone Tablets

As an aldosterone receptor antagonist, spironolactone tablets can inhibit aldosterone induced myocardial fibrosis and water sodium retention. This drug is suitable for patients with moderate to severe heart failure, and its combination with angiotensin-converting enzyme inhibitors can further reduce mortality. Regular monitoring of blood potassium levels is necessary during medication to avoid the occurrence of hyperkalemia.

4. Sacubitril Valsartan Sodium Tablets

Sacubitril Valsartan Sodium Tablets are angiotensin receptor enkephalinase inhibitors that dilate blood vessels, promote sodium induced urination, and inhibit myocardial remodeling through a dual mechanism. This drug is suitable for patients with chronic heart failure who have decreased ejection fraction and can significantly reduce the risk of cardiovascular death. Attention should be paid to the requirement of medication interval with angiotensin-converting enzyme inhibitors.

5. Dapagliflozin tablets

Dapagliflozin tablets, as sodium glucose cotransporter 2 inhibitors, were initially used for hypoglycemic therapy and have now been shown to improve the prognosis of heart failure. This drug reduces cardiac load through osmotic diuresis and metabolic regulation, and is suitable for heart failure patients with reduced ejection fraction. Attention should be paid to the possibility of increasing the risk of urinary and reproductive system infections. Patients with low ejection fraction should strictly limit their daily sodium intake to no more than 3 grams, avoid vigorous exercise, and engage in low-intensity aerobic activities such as walking, in addition to standardized medication. It is recommended to monitor weight changes daily and seek medical attention promptly if there is an increase of more than 2 kilograms within 3 days. Maintain a regular daily routine, avoid emotional excitement, quit smoking and limit alcohol consumption. Regularly review electrocardiogram, cardiac ultrasound and other examinations to evaluate cardiac function. Do not adjust medication dosage or discontinue medication on your own.