What is the reason for the high low shear viscosity of whole blood

The higher whole blood low shear viscosity may be related to factors such as blood concentration, erythrocytosis, hyperlipidemia, diabetes and chronic inflammation. Whole blood low shear viscosity is an important indicator reflecting blood fluidity, and a high value indicates an increase in blood viscosity, which needs to be further clarified in conjunction with other examinations.

1. Blood concentration

Dehydration or insufficient water intake can lead to blood concentration, a decrease in plasma volume, and a relative increase in red blood cells, resulting in an increase in whole blood low shear viscosity. This situation can be improved by drinking moderate amounts of water and supplementing electrolytes. If it is caused by diarrhea or vomiting, fluid imbalance should be corrected in a timely manner.

2. Increased red blood cells

In true polycythemia or secondary polycythemia, when the number of red blood cells per unit volume of blood exceeds the normal range, it directly leads to an increase in blood viscosity. The patient may have symptoms such as dizziness and flushing, which need to be diagnosed through bone marrow puncture and other examinations. If necessary, bloodletting therapy or medication treatment may be used. When cholesterol or triglyceride levels are abnormally elevated in hyperlipidemia, a large accumulation of lipids in the blood can alter plasma composition and increase blood flow resistance. Long term uncontrolled atherosclerosis may be induced. It is suggested to take low-fat diet, regular exercise and other lipid-lowering drugs such as atorvastatin calcium tablets.

4. In diabetes [SEP], the continuous increase of blood glucose can lead to the decrease of erythrocyte membrane deformability and the increase of glycosylated proteins in plasma. These changes will significantly improve blood viscosity. Patients should strictly monitor blood sugar, use metformin hydrochloride tablets and other drugs to control, and pay attention to preventing vascular complications of diabetes.

5. Chronic inflammation

Chronic inflammatory diseases such as rheumatoid arthritis and tuberculosis can stimulate the liver to produce large amounts of acute phase response proteins such as fibrinogen, promoting red blood cell aggregation. These patients need targeted treatment for the primary disease, such as using methotrexate tablets to control rheumatic activity, and regularly reviewing blood rheology indicators.

It is necessary to maintain a daily water intake of 1500-2000 milliliters, avoid prolonged sitting, and promote blood circulation by moving limbs every hour. Reduce the intake of animal organs and fried foods in diet, and increase foods rich in unsaturated fatty acids such as deep-sea fish and oats. People over 40 years old are recommended to have their blood rheology indicators tested annually. If accompanied by symptoms such as headaches and blurred vision, they should seek medical attention in a timely manner to assess the risk of cardiovascular and cerebrovascular diseases.