What is the reason for high shear rate of whole blood viscosity

The high shear rate of whole blood viscosity may be related to blood concentration, dyslipidemia, polycythemia, diabetes, hyperuricemia and other factors. Whole blood viscosity reflects blood flow resistance, and abnormal high shear values indicate a decrease in red blood cell deformability or increased aggregation, which needs to be comprehensively evaluated in conjunction with other indicators.

1. When dehydration or excessive sweating leads to fluid loss, a decrease in plasma volume will cause a relative increase in the proportion of blood cells, manifested as an increase in whole blood viscosity. This situation can be improved by moderate fluid replacement. It is necessary to maintain a daily intake of 1500-2000 milliliters of water to avoid not replenishing electrolytes in a timely manner after intense exercise.

2. Dyslipidemia

Elevated low-density lipoprotein cholesterol promotes lipid deposition in red blood cell membranes, reduces membrane fluidity, and thus affects red blood cell deformability. Patients with this condition often have total cholesterol levels exceeding 5.2 millimoles per liter. It is necessary to control the intake of animal organs and fried foods, and if necessary, follow medical advice to use atorvastatin calcium tablets or rosuvastatin calcium tablets to regulate blood lipids. When there is an abnormal increase in the number of primary or secondary red blood cells, the increase in the number of cells per unit volume of blood directly leads to an increase in viscosity. The patient may experience symptoms such as dark red complexion and dizziness, which require treatment through intravenous bloodletting or hydroxyurea tablets, while monitoring whether hemoglobin exceeds 160 grams per liter.

4. diabetes

Long term hyperglycemia will cause the increase of plasma fibrinogen and promote the aggregation of red blood cells. These patients have glycated hemoglobin levels exceeding 6.5%, and strict glycemic control is required. Medications such as metformin hydrochloride sustained-release tablets should be used, and fasting blood glucose should be monitored daily to maintain 4.4-7.0 millimoles per liter.

5. Hyperuricemia

The deposition of uric acid crystals on the blood vessel wall can trigger inflammatory reactions and alter the rheological properties of the blood. When the blood uric acid exceeds 420 micromoles per liter, it may affect the test results. It is recommended to limit the intake of seafood and beer. In the acute phase, follow the doctor's advice to use febuxostat tablets or benzbromarone capsules.

If abnormal whole blood viscosity is found, a complete set of hemorheological indicators should be rechecked, combined with blood routine and biochemical tests to determine the cause. It is recommended to adopt a low salt and low-fat diet in daily life, and engage in aerobic exercise such as brisk walking or swimming 3-5 times a week for at least 30 minutes each time. To avoid poor blood circulation caused by prolonged exposure to the same position, smokers should quit smoking as soon as possible to reduce damage to endothelial function.