What is the reason for high shear rate in whole blood viscosity

High whole blood viscosity may be related to factors such as blood concentration, dyslipidemia, polycythemia, diabetes, hyperuricemia, etc. Whole blood viscosity is an important indicator reflecting blood fluidity, and a high median shear value indicates an increase in blood viscosity. It is necessary to combine other examinations to clarify the cause.

Blood concentration is a common physiological cause, often caused by insufficient drinking water, excessive sweating, or diarrhea leading to fluid loss. Long term exposure to high temperatures and lack of timely hydration after intense exercise may also cause temporary blood viscosity. Adjusting the daily water intake to over 2000 milliliters to avoid prolonged dehydration can usually improve indicators. Dyslipidemia is the main pathological factor, and elevated low-density lipoprotein cholesterol can lead to increased plasma viscosity. These patients often have total cholesterol levels exceeding 5.2 millimoles per liter, and physical examination shows the formation of carotid plaques. It is necessary to control the intake of animal organs and fried foods, and if necessary, use blood lipid regulating drugs such as atorvastatin calcium tablets and simvastatin tablets according to medical advice. Erythrocytosis can significantly increase hematocrit, with primary patients often having hemoglobin levels exceeding 180 grams per liter, while secondary patients may be related to long-term hypoxia. Typical symptoms include facial flushing, headache, and dizziness, which need to be diagnosed through bone marrow puncture. Treatment can use hydroxyurea tablets to inhibit cell proliferation, or regular red blood cell sampling.

When blood sugar of diabetes patients continuously exceeds 7.0 mmol/L, glucose molecules will increase plasma osmotic pressure and accelerate erythrocyte aggregation. These patients are usually accompanied by an increase in glycated hemoglobin, which may lead to complications such as blurred vision and limb numbness. Standardized use of hypoglycemic drugs such as metformin hydrochloride tablets and glimepiride tablets is required, in conjunction with dietary and exercise management. When the blood uric acid in patients with hyperuricemia exceeds 420 micromoles per liter, urate crystals may alter the rheological properties of the blood. Commonly seen in people with a long-term high purine diet, episodic joint swelling and pain are typical manifestations. It is recommended to limit the intake of seafood and beer. In the acute phase, febuxostat tablets and benzbromarone tablets can be used to promote uric acid excretion.

It was found that the shear rate of whole blood viscosity was high, and blood rheology examination should be rechecked, combined with comprehensive judgment of blood lipids, blood glucose and other indicators. Maintaining a low salt and low-fat diet, engaging in 30 minutes of aerobic exercise daily, quitting smoking and limiting alcohol consumption can help improve blood rheology. If accompanied by symptoms such as dizziness and fatigue, it is necessary to seek medical attention promptly to check the risk of cardiovascular and cerebrovascular diseases.

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