The normal range of prothrombin time ratio is 0.8-1.2, and the specific value may vary slightly due to testing methods or laboratory standards. The prothrombin time ratio is an important indicator for evaluating the function of exogenous coagulation pathways, commonly used to monitor the effectiveness of anticoagulant therapy or diagnose coagulation dysfunction. The prothrombin time ratio is calculated through prothrombin time testing, and the ratio of the patient's prothrombin time to the normal control plasma prothrombin time is taken as the result. This indicator can reflect the activity levels of coagulation factors II, V, VII, and X. When using anticoagulant drugs such as warfarin, doctors usually control the ratio between 2.0-3.0 to achieve treatment goals. Fasting for 8-12 hours is required before testing to avoid high-fat diet affecting the results. Some laboratories will use international standardized ratios instead of traditional ratio reports to make the results of different laboratories comparable. Prolonged prothrombin time may indicate vitamin K deficiency, severe liver disease, or disseminated intravascular coagulation. When the ratio is abnormal, a comprehensive judgment should be made based on indicators such as activated partial thromboplastin time and fibrinogen.
Daily attention should be paid to maintaining a balanced diet, consuming moderate amounts of green leafy vegetables rich in vitamin K, but maintaining a stable intake during the use of anticoagulant drugs. Avoid excessive exercise that may cause external bleeding, and regularly check coagulation function. It is not advisable to drink alcohol or take drugs that affect coagulation function 24 hours before the test. If there are abnormal bleeding symptoms such as gum bleeding and subcutaneous bruising, it is necessary to seek medical attention in a timely manner to re-examine coagulation indicators.
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