What is the best way to reduce triglycerides and take some medicine

Reducing triglycerides can be achieved by adjusting lifestyle and medication, with commonly used drugs including fenofibrate, atorvastatin, and omega-3 fatty acid ethyl ester. The increase of triglyceride is usually related to improper diet, lack of exercise, obesity, diabetes, hypothyroidism and other factors.

1. Fenofibrate:

Fenofibrate belongs to the fibrate class of lipid-lowering drugs, which activates peroxisome proliferator activated receptors to reduce triglyceride synthesis and increase high-density lipoprotein levels. Suitable for patients with severe hypertriglyceridemia, who may experience gastrointestinal discomfort or muscle pain as side effects, and require regular monitoring of liver function.

2. Atorvastatin:

Atorvastatin, as a statin drug, mainly inhibits cholesterol synthase to improve blood lipid profile and has a significant effect on mixed hyperlipidemia. This medicine can simultaneously reduce low-density lipoprotein and triglycerides. During use, attention should be paid to the risk of rhabdomyolysis and avoid taking it with grapefruit.

3. Omega-3 fatty acids:

High purity omega-3 fatty acid ethyl ester directly reduces triglycerides by reducing the secretion of very low-density lipoprotein in the liver, suitable for patients with mild to moderate elevation. Daily intake of 2-4 grams can reduce triglycerides by 20-30%. Common dosage forms include soft capsules and prescription grade concentrated formulations.

4. Dietary control:

Reducing refined carbohydrates intake can significantly improve triglyceride levels, and it is recommended to replace white rice and flour with whole grains. Add no more than 25 grams of sugar per day, limit alcohol intake, and increase the proportion of foods rich in unsaturated fatty acids such as deep-sea fish and nuts.

5. Exercise intervention:

150 minutes of moderate intensity aerobic exercise per week can reduce triglycerides by 20%, and activities such as brisk walking, swimming, and cycling can enhance lipoprotein lipase activity. It is recommended to combine resistance training to improve basal metabolic rate, and supplementing protein after exercise can help maintain muscle mass. Triglyceride management requires long-term comprehensive intervention, and drug treatment should be carried out under the guidance of a doctor. Daily recommendations include adopting a Mediterranean diet pattern, with a focus on consuming olive oil, fish, vegetables, and legumes, and avoiding trans fatty acids. Maintain a 30 minute exercise routine at least 5 times a week and keep your weight within the normal BMI range. Regularly monitor the four indicators of blood lipids, and those with hypertension or diabetes need to control basic diseases simultaneously. Sudden onset of severe abdominal pain should alert to the possibility of acute pancreatitis and prompt medical attention should be sought.