Elevated eosinophils may be related to parasitic infections, allergic diseases, chronic inflammation, hematological disorders, endocrine disorders, and other factors. Eosinophils are a type of white blood cell, and an abnormal increase in their proportion usually indicates the presence of a specific pathological state in the body.
1. Parasitic infection:
Intestinal parasitic infections such as roundworms and hookworms can stimulate eosinophils to release histamine and other mediators. This type of infection is often accompanied by symptoms such as abdominal pain and malnutrition. Fecal egg testing can confirm the diagnosis, and deworming treatments such as albendazole can effectively control the infection.
2. Allergic diseases:
Type I hypersensitivity diseases such as allergic rhinitis and asthma can activate eosinophils. Patients often experience symptoms such as sneezing and skin itching. Serum IgE testing and allergen screening can assist in diagnosis, and antihistamines such as loratadine can alleviate symptoms. 3. Chronic inflammation: Chronic inflammatory diseases such as rheumatoid arthritis and ulcerative colitis can lead to sustained activation of eosinophils. These types of diseases typically have elevated C-reactive protein levels and require long-term control through immunosuppressive agents such as methotrexate. 4. Hematological disorders: Chronic myeloid leukemia, polycythemia vera, and other bone marrow proliferative diseases can directly cause an increase in eosinophils. Accompanied by symptoms such as splenomegaly and night sweats, bone marrow aspiration and genetic testing can provide a clear diagnosis, requiring targeted drug or chemotherapy intervention.
5. Endocrine disorders:
Endocrine diseases such as hypothyroidism and diabetes may indirectly affect basophils through metabolic disorders. This type of situation requires testing of thyroid hormones, blood glucose, and other indicators. Hormone replacement or hypoglycemic treatment can improve abnormal indicators. When an increase in eosinophils is detected, it is recommended to improve parasite screening, allergen testing, inflammatory markers, and bone marrow examination. Daily attention should be paid to dietary hygiene to avoid parasitic infections. People with allergies should reduce exposure to allergens such as pollen, dust mites, etc. Chronic disease patients should regularly monitor their blood routine. If accompanied by symptoms such as persistent fever and weight loss, timely hematological examination is necessary to rule out malignant diseases.
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