What if taking sildenafil doesn't work

The ineffectiveness of taking sildenafil may be related to poor drug absorption, improper timing of medication, psychological factors, insufficient dosage, or underlying diseases. Suggest adjusting medication methods, investigating potential causes, and changing treatment plans under the guidance of a doctor.

1. Medication malabsorption

High fat diet or alcohol consumption may delay the absorption of sildenafil, and taking it on an empty stomach is more effective. Patients with gastrointestinal disorders may experience medication absorption disorders and may try adjusting the interval between medication and meals. Some populations have faster drug metabolism, and individual differences need to be evaluated.

2. Inappropriate timing of medication

Sildenafil should be taken 30-60 minutes in advance, as taking it too early or too late can affect its efficacy. Aging may lead to delayed onset of medication, and elderly patients can take medication earlier appropriately. Avoid taking nitrate drugs together as it may counteract the therapeutic effect.

3. Psychological interference

Anxiety or depression can suppress physiological responses, and even medication may not be effective. The tense relationship between partners may increase psychological burden, and it is recommended to cooperate with psychological counseling. Long term stress can lead to abnormal hormone levels in the body, affecting drug sensitivity.

4. Dose needs to be adjusted

The initial dose of 25mg may be insufficient for some patients and needs to be increased to 50mg or 100mg after evaluation by a doctor. For patients with liver and kidney dysfunction, the dose needs to be adjusted to avoid metabolic abnormalities affecting the efficacy. Do not increase the dosage on your own as it may cause serious adverse reactions.

5. The existence of basic diseases

diabetes, hypertension and other chronic diseases will lead to vascular endothelial damage and reduce drug response. Low testosterone levels may require combined hormone therapy. Cardiovascular disease patients need to first control the primary disease before evaluating the medication plan.

It is recommended to record the details of medication reactions for doctors' reference, and try to improve blood circulation through regular sleep and moderate exercise. Consider replacing similar drugs such as Tadalafil and Vardenafil, or using a vacuum negative pressure device in combination. Patients with severe vascular lesions need to undergo surgical treatment such as penile vascular reconstruction. Daily supplementation with foods rich in arginine, such as nuts and deep-sea fish, can prevent excessive fatigue and mental stress. If there are visual abnormalities or sustained erections for more than 4 hours during medication, seek medical attention immediately.