When paranoid ideation is severe, it may lead to extreme behavior, loss of social function, or a risk of self harm or injury. Persecutive delusions belong to the spectrum disorder of schizophrenia, mainly manifested as the unfounded belief that one is being persecuted, and the severity is positively correlated with the systematic nature of delusional content and the probability of behavioral loss. If patients with paranoid ideation are not intervened in a timely manner, the delusional content may develop from a single suspicion to a complex and systematic one, such as expanding from believing that neighbors are eavesdropping to firmly believing in global organization joint surveillance. Patients may experience physical symptoms such as insomnia and anorexia due to excessive alertness, and some may adopt aggressive defensive behaviors such as carrying weapons or pre attacking imaginary enemies. Long term delusions can lead to social avoidance, loss of work ability, breakdown of family relationships, and even breaking the law due to extreme behavior.

A small number of patients may have comorbidities of depression or manic episodes, leading to suicidal tendencies. Some cases may refuse medical treatment or attack medical staff due to delusional content involving supernatural forces. In extremely severe cases, there may be a complete loss of practical testing ability and mandatory medical intervention is required. The longer the duration of delusions, the more difficult it is to reverse the damage to cognitive function in the brain, and early treatment is key. Patients with paranoid ideation should receive antipsychotic medication under the guidance of a psychiatrist, in conjunction with cognitive-behavioral therapy. Family members should avoid arguing with patients about delusional content, focus on observing signs of dangerous behavior, and take good care of dangerous items in the home. Regular follow-up visits to assess the condition, maintaining a regular schedule and moderate social activities can help delay functional decline. The social support system is crucial for rehabilitation, and community mental health services can provide long-term follow-up management.


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