What diseases can be detected by whole blood examination? CRP

The CRPC reactive protein in whole blood tests is mainly used to screen for inflammation, infection, and cardiovascular disease risk. Common abnormalities indicate pathological conditions such as bacterial infections, autoimmune diseases, trauma, or tumors.

1. Bacterial infection: A significant increase in

CRP is a typical sign of bacterial infection, with values often exceeding 50mg/L. Acute suppurative tonsillitis, pneumonia, urinary tract infections and other bacterial diseases can stimulate the liver to rapidly synthesize CRP, which is more sensitive than the white blood cell count in blood routine. For patients with postoperative fever, CRP dynamic monitoring can effectively distinguish between infectious fever and non infectious fever.

2. Identification of viral infection:

During viral infection, CRP usually increases slightly by 10-40mg/L, which is significantly different from bacterial infection. The identification accuracy of viral diseases such as hand, foot, and mouth disease, influenza, etc. can be improved by analyzing the proportion of lymphocytes in CRP combined with blood routine. However, EB virus and cytomegalovirus infections may result in false elevation of CRP.

3. Autoimmune diseases:

Rheumatoid arthritis, systemic lupus erythematosus, and other diseases have a sustained moderate increase in CRP levels of 20-60mg/L during the active phase. The combined detection of CRP and erythrocyte sedimentation rate can evaluate disease activity. When the increase in CRP is greater than that of erythrocyte sedimentation rate, attention should be paid to the possibility of co infection. The degree of sacroiliac joint inflammation in patients with ankylosing spondylitis is positively correlated with CRP levels.

4. Cardiovascular risk assessment:

hypersensitive CRPhs CRP can predict the risk of atherosclerosis, and the ideal value should be<1mg/L. When hs CRP continues to exceed 3mg/L, the risk of myocardial infarction increases by 2-4 times. The American Heart Association recommends including hs CRP in routine screening of high-risk populations for coronary heart disease, and combining it with lipid testing can optimize the risk assessment model.

5. Tumor monitoring:

Malignant tumors such as lymphoma, liver cancer and pancreatic cancer can cause a continuous increase of CRP>100mg/L. CRP is associated with tumor burden and malignancy, and postoperative abnormal CRP suggests the possibility of residual lesions. However, co infection factors need to be excluded, and it is recommended to make a comprehensive judgment based on imaging examinations such as PET-CT. Regular monitoring of CRP requires comprehensive interpretation in conjunction with other indicators. Maintaining a regular daily routine, a balanced diet such as increasing intake of anti-inflammatory foods such as deep-sea fish and nuts, and moderate exercise can help control chronic inflammation. Smoking and excessive drinking can significantly increase CRP levels, and it is recommended to avoid these behaviors 3 days before the physical examination. For those with persistent abnormalities, it is recommended to improve specialized examinations such as immunofixation electrophoresis and procalcitonin to clarify the cause.