Urinary protein 2+usually indicates abnormal renal filtration function, which may be caused by strenuous exercise, dehydration, urinary system infection, chronic kidney disease, diabetes nephropathy and other reasons.
1. Intense exercise:

High intensity exercise may lead to temporary proteinuria, changes in renal hemodynamics during exercise, and increased glomerular filtration membrane permeability. This physiological proteinuria usually disappears on its own after 24-48 hours of rest and does not require special treatment. It is recommended to replenish water promptly after exercise.
2. Dehydration state: When there is insufficient body fluid, urine concentration may cause false proteinuria positivity. Commonly seen in high-temperature work, diarrhea, or people with insufficient drinking water, normal urine routine can be restored through fluid replacement and rechecking. It is recommended to drink 1500-2000 milliliters of water daily and observe that the urine color should remain light yellow.
3. Urinary system infections:
Infections such as cystitis and pyelonephritis may be accompanied by an increase in urinary protein, which is related to the dysfunction of renal tubular reabsorption caused by inflammatory reactions. Typical symptoms include frequent urination, urgency, and burning pain during urination, requiring urine culture examination. The main treatment is antibiotics, and commonly used drugs include levofloxacin, cefuroxime, etc.

4. Chronic kidney disease:
Damage to the glomerular basement membrane can lead to persistent proteinuria, commonly seen in hypertensive nephropathy, IgA nephropathy, etc. The patient may have edema and increased nocturia, and blood creatinine and glomerular filtration rate need to be checked. Controlling blood pressure and limiting protein intake are key, and angiotensin-converting enzyme inhibitors should be used if necessary.
5. diabetes Nephropathy:
Long term hyperglycemia impairs the glomerular filtration barrier, with microalbuminuria in the early stage and overt proteinuria in the advanced stage. Patients need to monitor glycated hemoglobin and strictly control blood sugar. Treatment requires a combination of hypoglycemic drugs and renal protective drugs, such as SGLT-2 inhibitors.
If urinary protein 2+is found, morning urine should be rechecked to avoid testing during menstruation. Daily salt intake should be limited to no more than 5 grams to avoid a high protein diet that increases the burden on the kidneys. It is recommended to engage in 3-5 moderate intensity aerobic exercises per week, such as brisk walking, swimming, etc. Regularly monitor blood pressure and blood sugar levels, and individuals aged 40 and above should undergo annual kidney function tests. If accompanied by edema, foam urine or elevated blood pressure, it is necessary to timely seek medical advice from the nephrology department to improve the 24-hour quantitative detection of urinary protein.

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