Elevated thyroid function TSH may be caused by hypothyroidism, pituitary lesions, medication effects, iodine deficiency, or thyroiditis. TSH stands for thyroid stimulating hormone, and an increase in its level usually reflects insufficient secretion of thyroid hormones or abnormal thyroid function.
1. Hypothyroidism
Primary hypothyroidism is the most common cause of elevated TSH, which may be related to Hashimoto's thyroiditis, thyroid surgery, or radioactive iodine therapy. Patients often experience symptoms such as fatigue, fear of cold, and weight gain. Thyroid hormone replacement therapy such as levothyroxine sodium tablets is needed to improve function.
2. Pituitary lesions
Pituitary tumors or hypothalamic lesions may lead to abnormal increase in TSH secretion. At this time, although TSH is elevated, thyroid hormone levels may be normal or low. Pituitary MRI examination is required to confirm the diagnosis, and if necessary, medication such as bromocriptine tablets or surgical treatment may be used.
3. Drug effects
Lithium preparations, amiodarone, and other drugs may interfere with thyroid hormone synthesis, leading to feedback TSH elevation. Usually, it can gradually recover after stopping the medication or adjusting the dosage, and regular monitoring of thyroid function is required during the medication period.
4. Iodine deficiency
Long term insufficient iodine intake can affect thyroid hormone synthesis, and the body compensates by increasing TSH to stimulate the thyroid gland. It is more common in inland iodine deficient areas and can be supplemented by consuming iodized salt, kelp, etc. In severe cases, treatment with levothyroxine sodium tablets is necessary.
5. Thyroiditis
Subacute thyroiditis or postpartum thyroiditis and other inflammatory diseases may experience transient TSH elevation in the early stages, accompanied by thyroid pain or enlargement. Mild symptoms can heal on their own, and when pain is significant, ibuprofen sustained-release capsules can be used to alleviate symptoms.
If TSH is found to be high, a complete set of thyroid function tests should be rechecked and combined with thyroid ultrasound and other examinations to determine the cause. It is necessary to ensure a balanced diet in daily life, consume seafood in moderation to supplement iodine elements, and avoid excessive fatigue and mental stress. If diagnosed with hypothyroidism, long-term regular medication is required, and the dosage cannot be adjusted by oneself. Thyroid function should be rechecked every 3-6 months. Pregnant women with elevated TSH require timely intervention to avoid affecting fetal development.
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