What are the reasons for high eosinophil count in infants

Elevated eosinophils in infants are usually caused by allergic reactions, parasitic infections, drug reactions, skin diseases, immune abnormalities, and other reasons.

1. Allergic reactions:

When infants come into contact with allergens such as milk protein, pollen, or dust mites, the immune system releases substances such as histamine to stimulate an increase in eosinophils. Common manifestations include skin eczema, urticaria, or respiratory symptoms. breastfeeding mothers need to check for allergens in their diet, and formula feeding may consider switching to hydrolyzed protein milk powder.

2. Parasitic infections:

Intestinal parasitic infections such as roundworms and hookworms can directly stimulate the immune system to produce eosinophil responses. Infants may experience diarrhea, malnutrition, or perianal itching. Fecal routine examination can detect insect eggs, and deworming medication should be used under the guidance of a doctor.

3. Drug reactions:

Penicillin antibiotics, antiepileptic drugs, etc. may cause drug hypersensitivity reactions. If there is an increase in eosinophils accompanied by drug rash and fever after medication, the medication should be stopped immediately. Drug inducers usually have elevated IgE antibody levels, and skin prick tests may be necessary to confirm.

4. Skin diseases: Chronic skin inflammations such as atopic dermatitis and herpetic dermatitis can lead to local eosinophil infiltration. Red patches, exudation, and severe itching are common in the skin lesions, and the serum total IgE level is often significantly elevated. Keep the skin moist and avoid scratching to prevent secondary infections.

5. Immune abnormalities:

Congenital immunodeficiency diseases such as high IgE syndrome and eosinophilia can cause persistent elevation. These children are often accompanied by recurrent infections and delayed growth and development, and need to be diagnosed through genetic testing and bone marrow puncture.

For infants with high levels of eosinophils, it is recommended to maintain a clean living environment and regularly remove mites and dust; Breastfeeding mothers should avoid consuming high-risk allergenic foods such as seafood and nuts; Choose breathable cotton clothing to reduce skin friction; Timely vaccination to enhance immunity. If the value continues to exceed 15% or is accompanied by symptoms such as fever and difficulty breathing, special examinations such as allergen screening and parasite testing should be conducted in a timely manner. Daily diet and symptom changes can be recorded to provide reference for doctors' diagnosis.