Low osmotic pressure may cause symptoms such as dizziness, fatigue, nausea, and in severe cases, can lead to brain edema or organ dysfunction. Low osmotic pressure is mainly related to factors such as excessive water intake, electrolyte loss, renal dysfunction, endocrine disorders, and malnutrition.
1. Excessive water intake:
Drinking too much water in a short period of time can dilute the concentration of sodium ions in the blood, leading to a decrease in plasma osmotic pressure. This condition is common in patients with excessive hydration or psychogenic thirst after exercise, which may lead to hyponatremia, manifested as headaches, drowsiness, and even convulsions. It is recommended to drink a small amount of water multiple times in daily life, with a single water intake not exceeding 500 milliliters.
2. Electrolyte loss:
Continuous diarrhea, vomiting, or excessive sweating can cause the loss of electrolytes such as sodium and potassium. Digestive fluid contains a large amount of electrolytes, and patients with acute gastroenteritis can lose up to 200mmol of sodium ions daily through vomiting and diarrhea. It is necessary to take oral rehydration salts or intravenous electrolyte solutions in a timely manner.
3. Abnormal renal function:
Chronic kidney disease patients have decreased urine concentration function, more drainage than sodium excretion, and are prone to dilute hyponatremia. In the late stage of diabetes nephropathy, renal tubular dysfunction may occur, and the daily excretion of sodium in urine can reach more than 100mmol. Regular monitoring of blood sodium and urine osmotic pressure is required.
4. Endocrine disorders:
Syndrome of abnormal secretion of antidiuretic hormone (SIADH) can lead to reduced renal drainage and cause dilutive hyponatremia. When adrenal cortex function declines, aldosterone secretion is insufficient, sodium ion reabsorption is reduced, and blood sodium concentration can be lower than 130mmol/L, requiring hormone replacement therapy. 5. Malnutrition: Long term insufficient protein intake can lead to a decrease in plasma colloid osmotic pressure, which is common in extreme dieting or advanced cancer patients. When serum albumin is below 30g/L, water is prone to infiltrate tissue gaps from blood vessels, which may cause systemic edema and insufficient effective circulating blood volume.
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