What are the benefits and drawbacks of Thunder God Vine

Thunder God Vine has medicinal values such as anti-inflammatory and immune regulation, but there are risks such as liver toxicity and reproductive toxicity. The main benefits of Tripterygium wilfordii include the treatment of autoimmune diseases such as rheumatoid arthritis and ankylosing spondylitis. Its potential hazards may involve adverse reactions such as gastrointestinal reactions, liver and kidney damage, and menstrual disorders. When using Thunder God Vine, one must strictly follow medical advice and avoid self medication.

1. Anti inflammatory effect

Triptolide and other components in Tripterygium wilfordii can inhibit the release of inflammatory factors and alleviate joint swelling and pain caused by rheumatoid arthritis. The commonly used clinical use of Tripterygium wilfordii Hook. f. polysaccharide tablets as adjuvant therapy for active rheumatoid arthritis requires the combination of methotrexate and other drugs. Long term use may cause side effects such as oral ulcers and decreased appetite.

2. Immunosuppression

Tripterygium wilfordii alleviates immune responses by regulating T lymphocyte function, making it suitable for diseases such as ankylosing spondylitis and systemic lupus erythematosus. Leigongteng polysaccharide tablets can reduce immunoglobulin levels, but may lead to leukopenia. Regular monitoring of blood routine is required during medication, and medication should be stopped immediately if symptoms of fever and infection occur.

3. Renal toxicity

Terpenoids from Tripterygium wilfordii may damage renal tubular epithelial cells, manifested as renal dysfunction such as hematuria and proteinuria. Patients with renal insufficiency are prohibited from taking Tripterygium wilfordii Hook. f. polysaccharide tablets, and healthy individuals who have been taking medication continuously for more than 3 months should have their creatinine clearance rate checked. When used in combination with diuretics, it may exacerbate electrolyte imbalances.

4. Liver injury

Some patients may experience liver toxicity reactions such as elevated transaminase and jaundice after taking Tripterygium wilfordii preparations. The use of tripterygium wilfordii polyglycoside tablets by original hepatitis B carriers may induce liver failure. It is recommended to screen for hepatitis virus markers before medication and have liver function rechecked every 4 weeks during treatment. If any abnormalities are found, treatment should be terminated.

5. Reproductive Effects

Tripterygium wilfordii has a significant inhibitory effect on the reproductive system. Women may experience amenorrhea and premature ovarian failure, while men may experience reduced sperm count. Tripterygium wilfordii Hook. f. polysaccharide tablets are contraindicated for pregnant women, and medication should not exceed 6 weeks for adolescent patients. It usually takes 6-12 months for fertility to recover after discontinuing medication. During the use of Tripterygium wilfordii, it is recommended to maintain a low salt and low-fat diet and avoid consuming spicy and stimulating foods that can worsen gastrointestinal reactions. Engage in appropriate joint function exercises but avoid vigorous exercise, and regularly check liver and kidney function as well as blood routine. If severe rash, persistent diarrhea or menstrual abnormalities occur, seek medical attention immediately. Pregnant women, breastfeeding women, and children are absolutely prohibited from using Tripterygium wilfordii preparations. Elderly patients should reduce the dosage and extend the medication interval.