The principle and efficacy of mesodermal microneedles

Mesodermal microneedle is a cosmetic technique that promotes skin repair and regeneration through physical stimulation. Its principle is to use microneedles to create tiny channels on the surface of the skin, promoting the penetration of active ingredients and collagen production. Its main effects include improving skin quality, reducing fine lines, and shrinking pores.

1. Mechanical stimulation principle

Micro needle rollers or electric micro needle devices form micro pores with a diameter of 0.1-0.3 millimeters on the surface of the skin, which can activate the skin wound repair mechanism. Mechanical stimulation can stimulate platelets to release growth factors, initiate fibroblast proliferation, and disrupt epidermal barrier function, temporarily increasing skin permeability. This process does not damage the structure of the dermal mesh layer and belongs to minimally invasive stimulation.

2. Enhanced penetration of ingredients

The temporary channel formed by microneedles can allow cosmetic ingredients to directly reach the mesoderm, and the transdermal absorption rate can be increased by tens of times. Active substances such as hyaluronic acid, peptides, and vitamin C can bypass the stratum corneum barrier and target dermal cells. This delivery method avoids the first pass effect of oral medication and reduces the pain of traditional injections.

3. Collagen remodeling mechanism

Within 3-7 days after microneedle stimulation, the skin initiates a tertiary repair response: macrophages clear damaged tissue during the inflammatory phase, fibroblasts secrete type III collagen during the proliferative phase, and type I collagen gradually replaces it during the remodeling phase. This cascade reaction can thicken the dermis layer by 15-25% and improve connective tissue problems such as skin laxity and stretch marks.

4. Epidermal renewal effect

Microneedles promote the shedding of keratinocytes and accelerate the epidermal renewal cycle from 28 days to 14-18 days. The arrangement of the newly formed stratum corneum is tighter, and the distribution of melanin is more uniform, which has an improvement effect on pigmentation problems such as melasma and acne scars. At the same time, unblocking sebaceous gland ducts can reduce the colonization of Propionibacterium acnes.

5. Angiogenesis effect

Microneedle stimulation can induce the expression of vascular endothelial growth factor, promote capillary regeneration in the dermal papilla layer, and increase local blood flow by 30-50%. Improved microcirculation can provide more oxygen and nutrients to the skin, alleviate skin dullness, and have auxiliary therapeutic effects on vascular abnormalities such as rosacea.

Avoid contact with raw water within 24 hours after mesodermal microneedle care and cover the wound with medical repair dressings. Strict sun protection is required for 3 days after surgery, and choosing physical sunscreen is safer. The recommended treatment interval is 4-6 weeks, and for sensitive skin, it should be extended to at least 8 weeks. Daily use of moisturizing products containing ceramides and avoidance of alcohol based irritant skincare products. Individuals with active acne, herpes, or skin infection symptoms should defer treatment, while those with scar constitution should choose carefully.