If left untreated, paranoid ideation may lead to deteriorating interpersonal relationships, impaired social functioning, and even self harm or aggressive behavior. Paranoia is a spectrum disorder of schizophrenia, in which patients often believe out of thin air that they have been persecuted and need to control their symptoms through medication intervention and psychological therapy.

1. Interpersonal relationship breakdown
Patients with paranoid ideation who have not been treated for a long time will continue to doubt the goodwill of family, friends, or colleagues, and engage in frequent arguments, unfounded accusations, and other behaviors. Typical manifestations include refusing to answer phone calls, installing monitoring devices on doors and windows, and suddenly severing social relationships. This pathological suspicion often leads to divorce of spouses and alienation of friends, forming a vicious cycle of isolation.
2. Occupational dysfunction
Patients may believe that their colleagues conspired to frame them or that their clients intended to poison them, resulting in behaviors such as refusing to go to work and damaging work documents. Some patients will repeatedly complain to regulatory authorities about fabricated workplace persecution, ultimately leading to unemployment. Persistent delusions can also affect attention and judgment, making it difficult for patients to complete basic work tasks.
3. Deterioration of economic conditions
To prevent imagined persecution, patients often spend a lot of money installing anti-theft systems, frequently changing residences, or hiring bodyguards. Some people may suddenly withdraw all their deposits and hide them elsewhere, or even sell their assets to avoid non-existent threats. Some patients have lost their source of income and fallen into poverty due to their inability to work normally.

4. Legal Dispute Risk
When the delusional target involves a specific group of people, patients may engage in stalking, defamation, or violent behavior. There have been cases where patients have thrown stones on suspicion of poisoning their neighbors or accused doctors of murder, causing a scene in hospitals. These actions may lead to civil litigation or forced medical intervention, and in severe cases, criminal liability may be imposed.
5. Physical health damage
Patients who refuse to seek medical treatment may experience malnutrition due to prolonged hunger strikes on suspicion of food toxicity. Some people stay up day and night to avoid surveillance, leading to cardiovascular disease. Some patients with comorbid depressive symptoms may exhibit self harm behavior, and in extreme cases, may commit suicide. Continuous mental stress can also trigger psychosomatic diseases such as peptic ulcers. Patients with paranoid ideation should use antipsychotic drugs such as olanzapine and risperidone under the guidance of a psychiatrist, in conjunction with cognitive-behavioral therapy to correct erroneous beliefs. Family members should avoid arguing with patients about delusional content, but instead guide them to pay attention to real evidence and regularly accompany follow-up visits to adjust medication plans. Maintaining a regular schedule and moderate social interaction can help delay the progression of the disease, and early systemic treatment can help most patients recover their social function.

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