High sympathetic nervous system hyperhidrosis is usually associated with emotional stress, autonomic dysfunction, and other factors, and can be alleviated through medication intervention, psychological regulation, physical therapy, and other methods. Hyperhidrosis may be caused by genetic factors, endocrine disorders, anxiety disorders, hyperthyroidism, diabetes and other diseases. It is manifested as abnormal sweating in the palms, armpits or soles of the feet, which seriously affects social interaction and quality of life.

1. Medication Intervention
Anticholinergic drugs such as glycopyrrolate tablets and oxybutynin tablets can inhibit sweat gland secretion and should be used under the guidance of a doctor. Beta blockers such as propranolol tablets are suitable for anxiety induced hyperhidrosis, while sedatives such as alprazolam tablets are effective for emotional hyperhidrosis. Local use of aluminum chloride solution can temporarily block sweat gland ducts, but long-term use may irritate the skin.
2. Psychological regulation
Cognitive behavioral therapy helps patients identify and correct erroneous perceptions of stress, and relaxation training such as abdominal breathing can reduce sympathetic nervous system excitability. Mindfulness meditation reduces anxiety by focusing on the present moment, while biofeedback therapy uses instruments to train patients to autonomously control sweating reactions. Group psychotherapy can improve compensatory hyperhidrosis caused by social anxiety.
3. Physical therapy
iontophoresis therapy temporarily seals sweat glands with weak current and needs to be repeated weekly. Microwave coagulation can accurately destroy the sweat glands under the armpit, and the effect lasts for a long time. Botulinum toxin injection can block neurotransmitter transmission and has a significant effect on local sweating, but it needs to be regularly administered. Laser therapy is suitable for small areas of stubborn hyperhidrosis, and postoperative skin care needs to be strengthened.

4. Neuromodulation
Thoracic sympathetic nerve transection is suitable for severe hyperhidrosis, but may cause compensatory hyperhidrosis. Transcutaneous electrical nerve stimulation regulates autonomic balance through low-frequency currents and requires continuous treatment. Vaginal nerve stimulation is effective for systemic hyperhidrosis with comorbid anxiety and requires the implantation of a pulse generator.
5. Daily management
Wear breathable cotton clothing to reduce skin irritation, and use antiperspirants containing alum to control mild symptoms. Avoiding spicy foods and caffeine intake, regular exercise can help stabilize autonomic nervous system function. Maintain a suitable ambient temperature and carry a sweatshirt with you to deal with sudden sweating. Patients with sympathetic nervous system hyperhidrosis need to establish a healthy sleep routine and ensure sufficient sleep to regulate neurotransmitter balance. Adding whole grains and dark green vegetables rich in B vitamins to the diet can help maintain the stability of the nervous system. Avoid entering an air-conditioned room immediately after intense exercise in summer, as excessive temperature differences can worsen symptoms. In social situations, it is recommended to use antiperspirant products in advance and change clothes. In severe cases, it is recommended to seek professional psychological support. Regular follow-up to exclude secondary factors such as thyroid disease, combined with multiple treatment methods, yields better results.

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