Reasons for low levels of troponin creatine kinase

Low levels of troponin and creatine kinase are usually normal physiological phenomena, which may be related to long-term lack of exercise, malnutrition, hypothyroidism, drug effects, or genetic factors.

1. Long term lack of exercise:

Long term sitting or lack of physical exercise can lead to a decrease in muscle metabolism levels and a reduction in the synthesis of troponin and creatine kinase. The low indicators of this group of people are often accompanied by a decrease in muscle mass, but generally do not cause obvious symptoms. It is recommended to improve muscle condition through gradual aerobic exercises such as brisk walking, swimming, and resistance training. 2. Malnutrition: Insufficient protein intake or vitamin D deficiency can affect muscle tissue repair and metabolism, leading to decreased levels of troponin and creatine kinase. Commonly seen in patients with long-term dieting and digestive and absorption disorders. Increase the intake of high-quality proteins such as eggs, fish, and dairy products, and if necessary, measure serum albumin levels.

3. Hypothyroidism: Insufficient secretion of thyroid hormones can reduce systemic metabolic rate and affect the activity of muscle enzyme systems. These patients may have symptoms such as fear of cold and fatigue, and need to be diagnosed through five thyroid function tests. Sodium levothyroxine is commonly used as a substitute therapy in clinical practice, and after treatment, many indicators can return to normal.

4. Drug effects:

Some lipid-lowering drugs such as statins or immunosuppressants may inhibit muscle cell metabolism, leading to a decrease in the synthesis of related enzymes. If there is a decrease in indicators during medication and no muscle pain symptoms, there is usually no need for special treatment. It is recommended to regularly review the muscle enzyme spectrum and communicate medication plans with doctors.

5. Genetic factors:

A very small number of patients with congenital metabolic abnormalities have creatine kinase synthesis disorders, manifested as sustained low levels accompanied by muscle weakness symptoms. Diagnosed through genetic testing, such cases require nutritional support and rehabilitation training under the guidance of a specialist doctor. For asymptomatic individuals with low levels of troponin and creatine kinase, it is recommended to prioritize lifestyle adjustments for improvement. Ensure at least 30 minutes of moderate intensity exercise daily, such as cycling or yoga; Add high-quality protein sources such as lean meat and soy products to the diet; Avoid excessive dieting or selective eating. If accompanied by persistent fatigue, edema, or progressive decline in indicators, it is necessary to promptly investigate pathological factors such as thyroid disease. It is recommended to conduct joint testing of muscle enzyme spectrum, electrolytes, thyroid function and other indicators during regular physical examinations to comprehensively evaluate the metabolic status of the body.